Results 71 to 80 of about 1,084,168 (352)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The pollution haven hypothesis : a geographic economy model in a comparative study [PDF]
Although based on theoretical foundations, the pollution haven hypothesis stating that heterogenous environmental regulations between countries influence multinational firms' location decisions, has never been clearly proven empirically.
Natalia Zugravu, Sonia Ben Kheder
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Response to “Considering the Potential Benefits of Over-the-Counter Naloxone” by Evoy et al [Letter]
Integrated Pharmacy Research and Practice, 2021 Brian Fuehrlein VA Connecticut Healthcare System, West Haven, CT, USACorrespondence: Brian FuehrleinVA Connecticut Healthcare System, West Haven, CT 06516, USAEmail brian.fuehrlein@yale.edu View the original paper by Dr Evoy and ...
Fuehrlein B
doaj
Are Trump and Bitcoin Good Partners?
, 2017 During times of extreme market turmoil, it is acknowledged that there is a tendency towards "flight to safety". A strong (weak) safe haven is defined as an asset that has a significant positive (negative) return in periods where another asset is in ...
Bouoiyour, Jamal, Selmi, Refk
core
Characterization of Murine Breast Cancer Cell Lines for Anti-Cancer Vaccine [PDF]
, 2017 Breast cancer is the most commonly diagnosed cancer in women and the second leading cause of cancer death among women in the United States (1). While treatments involving radiation and chemotherapy currently exist, disease must be detected early in order
Frazier, Haven N
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A University Business School as an Entrepreneurial Ecosystem Hub
Technology Innovation Management Review, 2019 This article assesses the progress of a business school toward achieving the status of an entrepreneurial ecosystem hub with emphasis on the components related to entrepreneurial universities, entrepreneurship education, university business incubators ...
Haven Allahar, Ron Sookram
doaj +1 more source