Results 91 to 100 of about 375,401 (277)
Hawaii Geothermal/Cable Project map volume : southern Maui environmental data map : land ownership
1 map : grayscaleThe map shows the types of land ownerships in southern Maui, Hawaii: federal, state, county, military, Hawaiian Home Lands, and private ...
Hawaii Deep Water Cable Program
core +2 more sources
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Advanced Science, EarlyView.Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
Hawaii Deep Water Cable Program Phase II-C [PDF]
, 1987 Prepared by G. Krasnick and J. Mansur of Parsons Hawaii for Hawaiian Electric Company, Inc. and the State of Hawaii Department of Business and Economic Development.
Mansur, J., Krasnick, George
core
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
1 map : grayscaleThe map shows the locations of protected natural areas, endangered or threatened animals, endangered or threatened plants, sensitive habitats, and lower sensitivy species in southern Maui ...
Hawaii Deep Water Cable Program
core +2 more sources
International Journal of General Medicine, 2013 Michael Stiefel,1 Christoph Alexander Rüst,1 Thomas Rosemann,1 Beat Knechtle2 1Institute of General Practice and for Health Services Research, University of Zurich, Zurich, 2Gesundheitszentrum St Gallen, St Gallen, Switzerland Background ...
Stiefel M +3 more
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Hanging on the line – on the need to assess the risk to global submarine telecommunications infrastructure – an example of the Hawaiian "bottleneck" and Australia [PDF]
Natural Hazards and Earth System Sciences, 2009 National economies are becoming increasingly dependent on the global telecommunications system – and in particular, its submarine cable infrastructure.
D. Dominey-Howes, J. Goff
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Advanced Science, EarlyView.Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang +9 more
wiley +1 more source
Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography
Advanced Science, EarlyView.Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian +12 more
wiley +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source