Results 191 to 200 of about 65,509 (255)

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Corrigendum to 'Advances in the Basic Sciences in Thoracic Oncology in the Last 20 Years and Their Translational Impact' [Journal of Thoracic Oncology Volume 21 Issue 1 (2026) 41-76]. [PDF]

J Thorac Oncol
Carbone M, Amos C, Attanoos RL, Boeri M, Bueno R, Bunn PA, Chirieac LR, Cooper B, Fennell D, Galateau-Salle F, Giannakou L, Goparaju CV, Hassan R, Hofman P, Kris MG, Mao W, Minaai M, Mitsudomi T, Molina TJ, Montuenga LM, Nabeshima K, Passaro A, Peters S, Rajan A, Richardson DB, Robbins H, Rolfo C, Rudin CM, Samet JM, Scherpereel A, Schrump DS, Sozzi G, Taioli E, Visonà SD, Yang H, Yoshikawa Y, Zhao A, Pass HI.   +37 more
europepmc   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

Understanding Cancer Health Disparities. [PDF]

Cancers (Basel)
Zhang J, Du W, Deng Y, Yu H, Fei P.
europepmc   +1 more source

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

A pilot randomized controlled trial of an outreach intervention to improve depression treatment initiation among racial and ethnic groups. [PDF]

Gen Hosp Psychiatry
Simiola V, Ridout KK, Erickson C, Kazan R, Nie S, Adolfson MP, Simon GE, Miller-Matero LR.   +7 more
europepmc   +1 more source

A Mechanical Planar Chiral Rotaxane Induces Single‐Handed Helicity in a Twisted Perylene Diimide

Angewandte Chemie, EarlyView.
A mechanical planar chiral rotaxane (Rmp) is used to induce single‐handed helical chirality (M) in a perylene diimide chromophore, resulting in persistent circular dichroism (CD) and circularly polarised luminescence (CPL). ABSTRACT The twisting of chromophores such as perylene diimides (PDIs) into helical structures affords chiroptical properties from
Thomas E. Lawson, Denis Hartmann, Artemijs Krimovs, Qilong Sun, Robert Pal, Timothy A. Barendt   +5 more
wiley   +1 more source

Herping the African Continent: Alien Amphibians and Reptiles in Sub-Saharan Africa. [PDF]

Biology (Basel)
Kopij G.
europepmc   +1 more source

Diversity‐Oriented Two‐Step Annulative π‐Extension Enables Access to Structurally Complex Nanographenes

Angewandte Chemie, EarlyView.
Pd‐catalyzed C–H arylation of polycyclic aromatic hydrocarbons (PAHs) with various aryltrimethylsilanes enables the preparation of structurally complicated arylated PAHs, which can be further transformed to nanographenes in a manner of two‐step annulative π‐extension (APEX) reaction.
Honami Katsuragawa, Yoshifumi Toyama, Shota Mikawa, Kou P. Kawahara, Hideto Ito, Kenichiro Itami   +5 more
wiley   +1 more source

Pediatric Climbers Experience More Upper Extremity Injuries, Geriatric Climbers More Lower Extremity Injuries, and Increased Shoulder Trauma Associated With Male Individuals in an Emergency Department Analysis of Rock Climbing-Associated Musculoskeletal Injuries. [PDF]

Arthrosc Sports Med Rehabil
Alexio TZ, Lee PM, Kim NN, Agonias KB, Obana KK, Luzzi AJ, Weiss JM.   +6 more
europepmc   +1 more source