Results 251 to 260 of about 704,354 (307)

Targeting Fibrotic Scarring by Mechanoregulation of Il11ra1+/Itga11+ Fibroblast Patterning Promotes Axon Growth after Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
This study demonstrates that a hydrogel with mechanical properties matching the spinal cord directs fibroblast alignment, reshaping fibrotic scars into parallel matrices. A specific fibroblast subset mediates extracellular matrix remodeling through mechanotransduction, promoting axonal regeneration and neural reconnections, revealing potential ...
Longyou Xiao   +11 more
wiley   +1 more source

Novel Bioresorbable Bone Wax for Potentiated Hemostasis and Osteogenesis

open access: yesAdvanced Science, EarlyView.
The synthesized bioresorbable bone wax material for hemostasis and osteogenesis. The preparation process of the novel resorbable bone wax and its mechanism of accelerating coagulation and promoting osteoregeneration through blood cell aggregation. Abstract Orthopedic surgery faces dual challenges of uncontrolled bleeding and poor bone regeneration at ...
Longbao Feng   +10 more
wiley   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

open access: yesAdvanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang   +17 more
wiley   +1 more source

Proteomic Analysis of Sputum from Patients with Active Tuberculosis. [PDF]

open access: yesProteomes
Marcantonio E   +3 more
europepmc   +1 more source

Bioinspired Directional Hydrogel‐Based High‐Performance Flexible Sensor for Multiple Jumping Pattern Detection in Athletic Training

open access: yesAdvanced Science, EarlyView.
This study develops a bioinspired directional hydrogel (BDH) via flow‐induced alignment of polyvinyl alcohol and dispersed carbon nanotubes, enhanced by the immersion of natural moisturizing factors. The BDH exhibits superior mechanical strength, conductivity, and moisture retention, enabling high‐performance flexible sensors for precise motion ...
Hanqi Wang   +11 more
wiley   +1 more source

High‐Resolution Multiplexed Sequencing of Single‐Cell Full‐length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion

open access: yesAdvanced Science, EarlyView.
CBTi‐seq is reported, leveraging Tn5 transposase‐mediated molecular assembly of combinatorial barcodes and UMIs for high‐resolution multiplexed sequencing of the full‐length transcriptome in single cells. This approach achieves molecular resolution by end‐to‐end sequencing, enabling reconstruction of splice variants and accurate quantification of ...
Liyong He   +14 more
wiley   +1 more source

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