Results 91 to 100 of about 678,841 (321)

Interpreting Hazard Ratios: Insights from Frailty Models [PDF]

open access: yesarXiv, 2017
Hazard ratios are often used to evaluate time to event outcomes, but they may be hard to interpret. A particular issue arise because hazards are typically estimated conditional on survival, i.e.\ on left truncated samples. Then, hazard ratios from conventional models cannot be interpreted as counterfactual hazard ratios that are immediately relevant to
arxiv  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

THE WORMHOLE HAZARD

open access: yesTime and Matter, 2006
To predict the outcome of (almost) any experiment we have to assume that our spacetime is globally hyperbolic. The wormholes, if they exist, cast doubt on the validity of this assumption. At the same time, no evidence has been found so far (either observational, or theoretical) that the possibility of their existence can be safely neglected.
openaire   +3 more sources

The Hazards of Endpoints [PDF]

open access: yesJNCI Journal of the National Cancer Institute, 2010
of development, we would plant seeds from each variety and spray the sprouting plants with pesticide. We would drop from further development those varieties that seem adversely affected. In the next phase, we would plant seeds from those varieties still under consideration and pull up the stalks 8 weeks later to weigh the ears.
openaire   +3 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Hazards Analysis. Minor Hazards

open access: yes, 1961
An evaluation of the minor hazards associated with operation of the Experimental Gas Cooled Reactor is presented. (J.R.D.)
R S Miller, D Luse
openaire   +3 more sources

Evolution of Data-driven Single- and Multi-Hazard Susceptibility Mapping and Emergence of Deep Learning Methods [PDF]

open access: yesarXiv
Data-driven susceptibility mapping of natural hazards has harnessed the advances in classification methods used on heterogeneous sources represented as raster images. Susceptibility mapping is an important step towards risk assessment for any natural hazard.
arxiv  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Lethal Hazards of the Luteal Phase of the Menstrual Cycle [PDF]

open access: green, 1959
I. L. MacKinnon   +2 more
openalex   +1 more source

The dangers of hazards [PDF]

open access: yesToxicology Research, 2016
Abstract Concerns about the quality and reproducibility of scientific papers have emphasised the uncertainty of observations in the biological sciences. Focussing on this problem in the types of science that often underlie regulations affecting population exposures has clear implications for regulatory studies.
openaire   +3 more sources

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