Results 91 to 100 of about 634,600 (245)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Codification of Peaceful Coexistence

Boletín Mexicano de Derecho Comparado, 1968
John N. Hazard
doaj   +1 more source

Assessment of future risk of agricultural crop production under climate and social changes scenarios: A case of the Solo River basin in Indonesia

Journal of Flood Risk Management
Understanding the impacts of climate change and conversion of paddy field areas in the future on agricultural production is an essential part of flood‐risk management.
Badri Bhakta Shrestha, Mohamed Rasmy, Tomoki Ushiyama, Ralph Allen Acierto, Takatoshi Kawamoto, Masakazu Fujikane, Takafumi Shinya, Keijiro Kubota   +7 more
doaj   +1 more source

Breastfeeding Benefits and Resources: How do women become milk donors?

EDIS
This publication is intended for a general audience from all educational backgrounds. It explains the process of becoming a donor to the Mothers’ Milk Bank of Florida and why the criteria for being a donor screens for things that are often safe when ...
Angela Szymanski, Diana Hazard Taft
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

On the Nearshore Significant Wave Height Inversion from Video Images Based on Deep Learning

Journal of Marine Science and Engineering
Accurate observation of nearshore waves is crucial for coastal safety. In this study, the feasibility of extracting wave information from wave video images captured by shore-based cameras using deep learning methods was explored, focusing on inverting ...
Chao Xu, Rui Li, Wei Hu, Peng Ren, Yanchen Song, Haoqiang Tian, Zhiyong Wang, Weizhen Xu, Yuning Liu   +8 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Modelos de derecho socialista para el desarrollo

Boletín Mexicano de Derecho Comparado, 1983
John N. Hazard
doaj   +1 more source

Machine learning-based assessment of offshore wind farm impacts on soft-bottom benthic communities in the Shandong Peninsula

Scientific Reports
Offshore wind power, as a crucial component of clean energy, is rapidly expanding globally; however, the long-term impact mechanisms on marine benthic ecosystems remain unclear.
Lan Wang, Yongqiang Zhang, Xueji Gu, Liang Zhang, Haizhou Zhang, Kai Su, Chuanting Zhao   +6 more
doaj   +1 more source