Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Quantitative assessment of landslide hazard and risk at regional-scale: a case study from central Vietnam. [PDF]
Das R, Van Tien P, Wegmann KW.
europepmc +1 more source
Earthquake hazard and risk assessment tool using Monte-Carlo simulation techniques
Ch. Kaufmann, Schwarz, Jochen
openalex +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The Legal Profession, The Impact of Law and Legal Theory, Foreword [PDF]
Hazard, Jr., Geoffrey C.
core +1 more source
Ask the Experts: Veterans' Perspectives on Communicating About Airborne Hazard Exposures. [PDF]
Fix GM +8 more
europepmc +1 more source
Probabilistic tephra fallout hazard maps for Sangay volcano, Ecuador
Alessandro Tadini +11 more
openalex +1 more source
Empirical Study of Knowledge, Attitude and Practice towards to Radiation Health Hazards of Cell Phone: a Case Study on Medical Science Students [PDF]
Mansooreh Dehghani +3 more
openalex
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source

