Results 171 to 180 of about 3,726,940 (286)

Identification of Lagged Duration Dependence in Multiple Spells Competing Risks Models [PDF]

We show non-parametric identification of lagged duration dependence in mixed proportional hazard models for duration data, in the presence of competing risks and consecutive spells.
Guillaume HORNY, Matteo PICCHIO
core  

Beyond animal testing: An integrated framework for modern chemical hazard identification and risk assessment. [PDF]

Environ Sci Ecotechnol
Fan T, Yan Z, Feng C, Wu F.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

A HAZOP-based hazard identification model for urban gas accidents: Development and empirical validation. [PDF]

PLoS One
Tian B, Li H, Cui X, Hu Z, Zhou Z, Shi W.   +5 more
europepmc   +1 more source

Microbial Community Analysis and Food Safety Practice Survey-Based Hazard Identification and Risk Assessment for Controlled Environment Hydroponic/Aquaponic Farming Systems. [PDF]

Front Microbiol, 2022
Dong M, Feng H.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Data-driven FMEA approach for hazard identification and risk evaluation in digital health. [PDF]

Sci Rep
Waseem HM, Islam SU, Harrison S, Epiphaniou G, Matragkas N, Arvanitis TN, Maple C.   +6 more
europepmc   +1 more source

Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification. [PDF]

Front Toxicol, 2021
Thunga P, Truong L, Tanguay RL, Reif DM.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

A note on optimal commodity taxation with moral hazard and separable preferences [PDF]

In this paper we show that differential commodity taxation is superfluous in an economy with moral hazard and separable preferences.Moral Hazard, Separable Preferences, Optimal Commodity ...
Francesco Ruscitti, Luca Panaccione
core