Results 101 to 110 of about 98,530 (284)

Per‐ and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To explore whether biological levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting the overall effect and accounting for correlations among each PFAS – relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban   +14 more
wiley   +1 more source

The Extended Exponential Distribution and Its Applications

open access: yesJournal of Statistical Theory and Applications (JSTA), 2018
We introduce a new three-parameter extension of the exponential distribution called the odd exponentiated half-logistic exponential distribution. Various of its properties including quantile and generating functions, ordinary and incomplete moments, mean
Ahmed Z. Afify   +2 more
doaj   +1 more source

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao   +12 more
wiley   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman   +6 more
wiley   +1 more source

Using Quantile Regression for Duration Analysis [PDF]

open access: yes
Quantile regression methods are emerging as a popular technique in econometrics and biometrics for exploring the distribution of duration data. This paper discusses quantile regression for duration analysis allowing for a flexible specification of the ...
Fitzenberger, Bernd, Wilke, Ralf A.
core  

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

open access: yesBMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen   +9 more
wiley   +1 more source

The spread of non‐native species

open access: yesBiological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock   +16 more
wiley   +1 more source

New lifetime Shanker Weibull distribution: Structure and Properties

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences
This paper introduces a new model with two parameters titled “Shanker Weibull distribution". This distribution is obtained by merging the Shanker distribution with a scale of one parameter and the Weibull distribution with a shape parameter.
Maysaa Jalil Mohammed   +2 more
doaj   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

open access: yesBiological Reviews, EarlyView.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman   +4 more
wiley   +1 more source

Neutrosophic moment exponential distribution: properties and modeling of child mortality rate data

open access: yesAIMS Mathematics
This research extends traditional statistical distribution theory, which often neglects issues such as ambiguity, imprecision, or indeterminacy. The primary aim is to develop the neutrosophic moment exponential distribution as a refined version of the ...
Ghadah Alomani   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy