Results 121 to 130 of about 193,848 (310)
THE USE OF LIABILITY RULES IN CONTROLLING HAZARDOUS WASTE ACCIDENTS: THEORY AND PRACTICE [PDF]
Resource /Energy Economics and Policy,
Opaluch, James J.
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Our Toxic World A guide to hazardous substances in our everyday lives
, 2011 Max Martin
openalex +2 more sources
Trouble in Toyland: The 23rd Annual Toy Safety Survey [PDF]
, 2008 Details findings on deaths and injuries from and toxic chemicals in toys, with a focus on lead and phthalates. Includes tips for consumers and recommendations for policy makers and the Consumer Product Safety Commission.
Edmund Mierzwinski, Liz Hitchcock
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Book Review of Jeffrey W. Vincoli, Risk Management for Hazardous Chemicals (1996) and Andre R. Cooper, Sr., Cooper\u27s Toxic Exposures Desk Reference (1997) [PDF]
, 1997 Book reviews for the following: Jeffrey W. Vincoli, Risk Management for Hazardous Chemicals (2 vols. CRC Lewis Publishers 1996). Acknowledgments, author, Chemical Abstracts Number index, chemical name index, introduction, preface, references, structure ...
Field, Thomas G., Jr.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Federal Regulation of Non-Nuclear Hazardous Wastes: A Research Bibliography [PDF]
, 1983 The identification of nonlinear systems by the minimization of a predictionerror criterion suffers from the problem of local minima. To get a reliableestimate we need good initial values for the parameters.
Danner, Richard A.
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