Results 161 to 170 of about 602,440 (286)

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Accidental and intentional poisonings in Colombia (2015-2023): Social and territorial inequalities affecting public health. [PDF]

Toxicol Rep
Fuentes-Fabra EE, Saenz-Ruiz M, Arrázola Díaz JJ.   +2 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Brief transdiagnostic cognitive behavioral therapy and expressive writing for hazardous drinking and posttraumatic stress symptoms among sexual and gender minority adults: Pilot trial protocol. [PDF]

Contemp Clin Trials Commun
Jaipuriyar V, Behari K, Rashkovsky K, Girard R, Sherman AL, Chasten N, Epshteyn GG, Lee J, Helminen EC, Scheer JR.   +9 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Sex Differences in the Association Between Drinking Motives, Protective Behavioral Strategies, and Alcohol Outcomes in a Hazardous Drinking College Sample. [PDF]

Subst Use Misuse
Hardee JE, Paige KJ, Ekves ZD, Kardan O, McCurry KL, Martz ME, Cope LM.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Lessons Learned from Implementing a Centrally Organized, Cross-Sectoral, Patient-Centered Treatment Coordination System for Hazardous Substance Use and Substance Use Disorders: The Randomized Controlled ASSIST Study.

Eur Addict Res
Röhrig J, Sutter L, Prestin E, Müller-Schoch VE, Debler-Ognjenovic A, Schippers G, Broekman TG, Rademacher L, Krausz M, Choi F, Mueller-Stierlin AS, Cabanis M.   +11 more
europepmc   +1 more source

A hemispheric commitment to mental health: from declaration to measurable results. [PDF]

Lancet Reg Health Am
Oliveira E Souza R, Martinez Piedra R.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source