Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Application of Graphene and its Derivatives in Detecting Hazardous Substances in Food: A Comprehensive Review. [PDF]
Front Chem, 2022 Pei J +9 more
europepmc +1 more source
Measuring Damages to Marine Natural Resources from Pollution Incidents under CERCLA: Applications of an Integrated Ocean Systems/Economic Model [PDF]
Several pieces of federal environmental regulation establish strict liability for damages from spills of oil and hazardous substances. This paper discusses the Natural Resource Damage Assessment Model for Coastal and Marine Environments (NRDAMICME ...
French, Deborah +3 more
core +1 more source
Neurobehavioral risk factors influence prevalence and severity of hazardous substance use in youth at genetic and clinical high risk for psychosis [PDF]
, 2023 Carolyn Amir +17 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
[Risk communication for protection against hazardous substances in the workplace]. [PDF]
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 2022 Pipke R, Wilmes A.
europepmc +1 more source
ATSDR public health investment : Tennessee [PDF]
CDC/ATSDR support helps Tennessee reduce exposures to hazardous substances in the environment Tennessee is one of 25 states using ATSDR cooperative agreement funds to help build their capacity to assess and respond to site-specific issues involving human
core
Trouble in Toyland: The 23rd Annual Toy Safety Survey [PDF]
, 2008 Details findings on deaths and injuries from and toxic chemicals in toys, with a focus on lead and phthalates. Includes tips for consumers and recommendations for policy makers and the Consumer Product Safety Commission.
Edmund Mierzwinski, Liz Hitchcock
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Spatiotemporal Evaluation of Water Quality and Hazardous Substances in Small Coastal Streams According to Watershed Characteristics. [PDF]
Int J Environ Res Public Health, 2022 Lee HS +6 more
europepmc +1 more source