Results 131 to 140 of about 238,148 (334)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Changes in Intestinal Microbial Community of the Black Tiger Shrimp Penaeus monodon in Response to Triclocarban Exposure

open access: yesBiology
Triclocarban (TCC), a synthetic antimicrobial compound prevalent in personal care products, has emerged as a typical contaminant in aquatic ecosystems.
Yafei Duan   +5 more
doaj   +1 more source

A plan development process for solid and hazardous waste management in the Manawatu-Wanganui region: a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy at Massey University [PDF]

open access: yes, 1992
This thesis uses elements of the strategic and integrated planning process models to develop a planning process for solid and hazardous waste management for use by a New Zealand regional council.
Robson, Bridget
core  

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

In silico prediction of carcinogenic mechanisms induced by mixture of toxic substances from E-waste dust

open access: yesEcotoxicology and Environmental Safety
Humans are constantly exposed to low doses of various metals and organic compounds in electronic waste (e-waste) recycling areas. Although these substances individually have been identified as environmental carcinogens that influence the onset and ...
Xue Chen, Renjie Xu, Min Jiang
doaj   +1 more source

Environmental Risk Analysis: Problems and Perspectives in Different Countries [PDF]

open access: yes, 2002
The authors discuss various industrial accidents, which have led to growing concerns about the potential hazards and risks involved in chemical process ...
Gurjar, Bhola Ram, Mohan, Manju
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Ensuring a Bright Future for Children's Environmental Health

open access: yesAnnals of Global Health, 2016
William A. Suk, Peter D. Sly
doaj   +1 more source

Tracking Chart 2005 Fifth & Pacific, China 02021551D [PDF]

open access: yes, 2005
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core   +1 more source

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