Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura+7 more
wiley +1 more source
Development of a new QSPR based tool to predict explosibility properties of chemical substances within the framework of REACH and GHS [PDF]
International audienceThe new European régulation of Chemicals named REACH (for "Registration, Evaluation and Authorization of Chemicals") turned out in the practical registration phase in December 2008.
Adamo, Carlo+3 more
core +1 more source
Control of Hazardous Substances at Small Workplaces
Lots of chemicals are produced in chemical industry and used everywhere as convenient and indispensable materials in daily life and industry. Moreover, many new chemicals are needed to produce competitive new goods such as new medicines, new dyestuffs, new agricultural chemicals and others.
openaire +4 more sources
Amyotrophic Lateral Sclerosis as a Multistep Process in the United States: A Population‐Based Study
ABSTRACT Background Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease that typically results in death within 3–5 years from symptom onset. However, little is known about the environmental exposures, clinical aspects, or social determinants of health factors that may be associated with the disease.
Jasmine Berry+7 more
wiley +1 more source
Environmental impact of cadmium: a review by the Panel on Hazardous Trace Substances.
Michael Fleischer+6 more
openalex +1 more source
Patterns of Dermal Exposure to Hazardous Substances in European Union Workplaces [PDF]
Rajadurai Rajan-Sithamparanadarajah+8 more
openalex +1 more source
International Environmental Justice on Hold: Revisiting the Basel Ban from a Philippine Perspective [PDF]
Nineteen years after the Basel Ban was adopted it still has not garnered the necessary ratifications to enter into force. This article aims to revisit the Basel Ban and understand it from the perspective of a developing country, particularly the ...
Gutierrez, Richard
core +1 more source
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut+11 more
wiley +1 more source
Naïve (CD4+CD45RA+) T Cell Subpopulation is Susceptible to Various Types of Hazardous Substances in the Workplace [PDF]
Takeshi Tanigawa+2 more
openalex +1 more source
Ensuring a Bright Future for Children's Environmental Health
William A. Suk, Peter D. Sly
doaj +1 more source