Results 181 to 190 of about 567,546 (293)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Using an Electronic Self-Administered Survey Among First Responders to Evaluate the Potential Human Health Effects of Hazardous Substances Released as a Result of a Train Derailment Incident-East Palestine, Ohio, USA, February-March 2023. [PDF]

Disaster Med Public Health Prep
Crisp CA, Parasram VD, Shi DS, Omari A, Madera-Garcia V, Faherty EAG, Dulcey M, Burr K, Gichuhi B, Goldsworthy LA, Dowell CH, Chiu SK, Dickerson K, Dewart CM, Watkins SM, Harduar-Morano L, Babich R, Shugart J, Orr MF.   +18 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Rapid Screening for Hazardous Substances with Regulatory Differences in Milk Between Countries Using Ultra-High Performance Liquid Chromatography Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry. [PDF]

Foods
Guo Q, Zhang J, Shao B, Yin J, Yang Y, Yang Y.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Identification and Removal of Pollen Spectral Interference in the Classification of Hazardous Substances Based on Excitation Emission Matrix Fluorescence Spectroscopy. [PDF]

Molecules
Zhang P, Du B, Xu J, Wang J, Liu Z, Liu B, Meng F, Tong Z.   +7 more
europepmc   +1 more source

Evaluation of the impact of construction products on the environment by leaching of possibly hazardous substances. [PDF]

Environ Sci Eur, 2018
Bandow N, Gartiser S, Ilvonen O, Schoknecht U.   +3 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Diagnosis on Transport Risk Based on a Combined Assessment of Road Accidents and Watershed Vulnerability to Spills of Hazardous Substances. [PDF]

Int J Environ Res Public Health, 2018
Machado ER, Valle Junior RFD, Valle Junior RFD, Pissarra TCT, Siqueira HE, Sanches Fernandes LF, Pacheco FAL.   +6 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source