Results 61 to 70 of about 567,546 (293)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Debris capture during in-water cleaning of ship biofouling
Ship biofouling interferes with vessel operations and spreads non-indigenous species. While in-water cleaning (IWC) with debris capture is increasingly promoted as a management strategy, key elements remain poorly defined, including which materials must ...
Mario N. Tamburri +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Trojan seahorse: neglecting biofouling management of vessel niche areas
Biofouling has detrimental impacts on vessel operations, greenhouse gas emissions, and marine environmental, economic, social, and cultural values through the spread of non-indigenous species.
Eugene T. Georgiades +3 more
doaj +1 more source
Made available in DSpace on 2007-09-08T22:22:31Z (GMT). No. of bitstreams: 1 RR-E04.PDF: 5216597 bytes, checksum: 83178c68d6ef36bb2e15a314e06ba29c (MD5) Previous issue date ...
Rainson, Felicia, Costello, Kenneth W.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Safe storage of household substances to prevent child poisoning
Aim: The objective was to determine whether hazardous substances are safely stored in households. Design: A descriptive cross-sectional study was performed. Methods: The sample comprised 300 parents of children attending 20 selected kindergartens.
Ilona Plevová, Markéta Nedělová
doaj +1 more source
Psychological responses to hazardous substances [PDF]
prepared by Pamela Tucker.Includes bibliographical ...
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

