Results 81 to 90 of about 652,688 (313)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Cyber-Security Hazards in Society
, 2014 Cyber-security hazards in society are viewed in the context of tensions, disasters, and development opportunities. The tension is essentially that between the physical and spiritual world as we know it and the challenge given by virtual cyberspace to ...
Maitland Hyslop, Hyslop, Maitland
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Applied SciencesProlonged exposure to high-intensity noise environments in urban rail transit systems can negatively impact the health and work efficiency of drivers. However, there is a lack of comprehensive understanding of the noise pattern and, therefore, effective ...
Lu Huang +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
City of Beaverton natural hazards mitigation plan [PDF]
, 2003 364 pp. Includes maps, charts and figures in single file. Published November, 2003. Captured June 1, 2006.The Mitigation Plan contains background on the purpose of the plan, the methodology used to develop the plan, a profile of Beaverton, chapters on ...
Oregon Natural Hazards Workgroup +1 more
core
EFSA BIOHAZ Panel (EFSA Panel on Biologicial Hazards), 2013. Scientific Opinion on the public health hazards to be covered by inspection of meat (solipeds) [PDF]
, 2013 A risk ranking process identified Trichinella spp. as the most relevant biological hazard in the context of meat inspection of domestic solipeds.
EFSA Panel on Biological Hazards (BIOHAZ)
core +1 more source
Evaluation of the Occupational Risk Associated to Work Environment In Ferrous Metallurgy
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2019 Work environment present risk factors due to chemical pollution of ambient air with dust, smoke, fumes, vapors, mists and gases. Moreover physical risk factors (related to noise, lighting, temperature, vibration, humidity, radiation) lead to hazards with
Tamara RADU, Anișoara CIOCAN
doaj
BIOLOGICAL HAZARDS AND DISASTER RISK: COMPLEXITY OF CAUSES AND SOLUTIONS, AND OVERVIEW OF MANAGEMENT IMPLICATIONS [PDF]
Transactions of the VŠB: Technical University of Ostrava, Safety Engineering SeriesAdaptation and changes to the management of infectious diseases result from human research, knowledge gathering, interpretation and applications. Findings from the current study clearly point to the nature of the policy and disaster risk management ...
Crystal May BROWN +2 more
doaj +1 more source