Results 61 to 70 of about 12,863 (94)

Abstract 3697: Modulation of Nicotinamide N-Methyl Transferase (NNMT) expression in TNBC is associated with altered cell membrane cholesterol levels

Cancer Research, 2023
Introduction: Cancer cells often develop a program of metabolic adaptability and epigenetic remodelling to promote gene expression changes causing cancerous cell proliferation and invasion.
Woei-Yaw Chee, D. N. Dolcen, Lynda Bennett, S. Conzen   +3 more
semanticscholar   +1 more source

Abstract 3697: Exploiting patient-derived xenografts and organoids to tackle apoptotic dependencies in EGFR-inhibited colorectal tumours

Cancer Research, 2022
Treatment with EGFR-targeted therapies, such as the EGFR monoclonal antibody cetuximab, has improved the outcome of patients with metastatic colorectal cancer (mCRC). However, EGFR inhibition is mainly cytostatic and does not lead to tumor eradication:
S. Leto, Irene Catalano, Martina Ferri, V. Vurchio, F. Cottino, E. Zanella, F. Sassi, Giorgia Migliardi, A. Bertotti, L. Trusolino   +9 more
semanticscholar   +1 more source

Federico Donelli, Turkey in Africa: Turkey’s strategic involvement in sub-Saharan Africa. London: I. B. Tauris (hb £85 – 978 0 7556 3697 6; pb £28.99 – 978 0 7556 3701 0). 2021/2022, 224 pp.

Africa, 2022
autonomous vis-à-vis mediated elite discourses (such as politicians’ stigmatization of ‘homosexuals’ in their speeches). Yet the clunky, encompassing notion of public opinion leads Newell to tack constantly between generalizing statements and an ...
Yusuf Kenan Küçük
semanticscholar   +1 more source

Abstract 3697: Cell-free DNA fragmentome dynamics as a biomarker for immune-checkpoint inhibition in advanced carcinoma

Cancer Research
Immune-checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but a large proportion of patients is resistant to the treatment. Genome-wide cfDNA fragmentation profiles (fragmentome) represent a promising non-invasive approach able to ...
Linh Nguyen Phuong, F. Fina, Romain Zakrajsek, L. Greillier, Pascale Tomasini, J. Deville, A. Boutonnet, F. Ginot, Jean-Charles Garcia, Sébastien Salas, Sébastien Benzekry   +10 more
semanticscholar   +1 more source

Receptor Expressed in Lymphoid Tissue (RELT) induces death in cancer cells, is upregulated in macrophages in response to tumor-conditioned medium and can translocate to the nucleus 3697

Journal of Immunology
Receptor Expressed in Lymphoid Tissues (RELT) is a Tumor Necrosis Factor Receptor family member with two paralogs, RELL1 and RELL2 (collectively known as RELTfms).
E. D. Cho, Luke Cho, Maryann Batiste, Bethany Joy, Cara K. Yee, Ashley Christensen, Hannah Chang, Ihab Abed, Kailey Nguyen, Brittany Gillespie, M. Senderovich, Ai-Vy Le, Frank Hoang, Eslam Mohamed, John K. Cusick   +14 more
semanticscholar   +1 more source

Abstract 3697: High PD-L1 expression and targetable mutations occur independently in NSCLC and are not influenced by smoking or race

Clinical research, 2018
Background: Targeted therapies such as EGFR tyrosine kinase inhibitors (TKIs), and immunotherapy (IO) with PD-L1 inhibitors have revolutionized first-line treatment options for advanced non-small cell lung cancer (NSCLC).
N. Choudhury, Mansooreh Eghtesad, John F. Cursio, Sabah Kadri, Lauren L. Ritterhouse, J. Segal, A. Husain, J. Patel   +7 more
semanticscholar   +1 more source

#3697 Integrating crescent characteristics, vascular lesions, and podocyte injury into the MEST-C framework: enhanced risk stratification in IgA nephropathy

Nephrology, Dialysis and Transplantation
IgA Nephropathy (IgAN) remains a leading cause of chronic kidney disease and end-stage kidney disease globally. While the MEST-C framework has significantly advanced risk stratification, certain histopathological features, including crescent ...
José Soares, A. Carnevale, Ana Rita Pereirinha Ramos, Rodolfo Almeida, Madalena Borges, F. Caeiro, M. Góis, Helena Sousa, Cristina Rego de Freitas Mendes Jorge   +8 more
semanticscholar   +1 more source

Closure of Cases (3099, 3379, 3437, 3516, 3651, 3652, 3677, 3697, 3734)

Bulletin of Zoological Nomenclature, 2018
Case 3099: Titanodamon johnstonii Pocock, 1894 (currently Damon johnstonii: Arachnida, Amblypygi): proposed conservation of the specific name. (Case 3099). P. Weygoldt.
Iczn Iczn
semanticscholar   +1 more source

Abstract 3697: Proof-of-concept study to enumerate large oncosomes using the RareCyte CTC platform

Cancer Research
Introduction: Large oncosomes (LO) are produced by tumor cells and can be detected in blood from cancer patients. The clinical utility of enumerating and characterizing LOs along with CTCs has been demonstrated, especially in settings where CTC counts ...
Eszter Papp, Jo Vandesompele, Peter Vermeulen, L. Dirix, Mark Kockx   +4 more
semanticscholar   +1 more source

Association of atherogenic index of plasma and its modified indices with stroke risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a longitudinal analysis based on CHARLS

Cardiovascular Diabetology
The association between the atherogenic index of plasma (AIP), its modified indices (such as AIP-waist circumference [AIP-WC], AIP-waist-to-height ratio [AIP-WHtR], AIP-body mass index[AIP-BMI]), and incident stroke in individuals with cardiovascular ...
Xiaoyan Wang, Pengfei Wen, Yun Liao, Tao Wu, Lin Zeng, Yuxing Huang, Xiaomei Song, Zhen Xiong, Lisha Deng, Dingjun Li, Shuchuan Miao   +10 more
semanticscholar   +1 more source