Results 131 to 140 of about 177,964 (245)

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

Triacylglycerol‐Based Insulin Resistance Indices and Post‐Transplantation Diabetes Mellitus After Liver Transplantation

open access: yesLipids, EarlyView.
ABSTRACT Background: Post‐transplant diabetes mellitus (PTDM) is a common complication following liver transplant (LT) and is associated with adverse outcomes. The triacylglycerol‐glucose product (TyG) and the triacylglycerol‐to‐high‐density lipoprotein (HDL) cholesterol ratio (TAG/HDL‐c) are indices that can serve as triacylglycerol‐based proxies for ...
Mateo Chvatal‐Medina   +9 more
wiley   +1 more source

The Role of Obesity in the Association Between Alcohol Consumption and HDL‐c Levels: Baependi Heart Study

open access: yesLipids, EarlyView.
ABSTRACT Cardiovascular diseases (CVD) are a leading cause of global mortality, with dyslipidemia playing a central role in their pathogenesis. The influence of alcohol consumption on lipid profiles, particularly high‐density lipoprotein cholesterol (HDL‐c), in relation to obesity status remains insufficiently explored.
Larissa Esthefani Barros Cirino   +6 more
wiley   +1 more source

Lipid Profile in Primary Aldosteronism: Cross‐Sectional and Post‐Treatment Analyses

open access: yesLipids, EarlyView.
ABSTRACT The relationship between primary aldosteronism (PA) and lipid metabolism remains controversial, with inconsistent findings reported in the literature. This study aimed to clarify PA's impact on the lipid profile using both a cross‐sectional comparison with essential hypertension (EH) controls and a longitudinal within‐patient pre‐post ...
Meriem Yazidi   +7 more
wiley   +1 more source

Causal Link Between Obstructive Uropathy, Estradiol, and Risk of Breast Cancer: Insights From Observational Evidence and Genetic Association Analyses

open access: yesMedicine Advances, EarlyView.
Based on the observational analysis of UK Biobank clinical data, urinary tract obstruction showed a significant negative association with breast cancer risk, accompanied by substantially lower systemic estradiol levels in individuals with obstruction.
Hailu Wang   +7 more
wiley   +1 more source

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