Results 201 to 210 of about 27,244 (246)

Metabolic clearance rate of insulin across the glucose tolerance spectrum by race and ethnicity in youth with obesity

open access: yesObesity, EarlyView.
Abstract Objective Despite β‐cell failure in youth with dysglycemia (i.e., impaired glucose tolerance [IGT] and type 2 diabetes), fasting insulin (FI) concentrations are elevated. Herein, we examined the following: 1) metabolic clearance rate of insulin (MCRI) in youth with obesity and normal glucose tolerance (NGT) versus those with IGT versus those ...
Wonhee Cho   +6 more
wiley   +1 more source

Fat taste sensitivity in women with obesity: transcriptomic analysis of fungiform papillae before and after bariatric surgery

open access: yesObesity, EarlyView.
Abstract Objective Fat taste sensitivity has been implicated in long‐term weight loss after bariatric surgery. Unexpectedly, improvement of orosensory fat acuity was not systematic in operated patients. Methods Obesity‐induced alterations of gene expression in gustatory papillae having been recently reported, we have explored the fungiform ...
Arnaud Bernard   +5 more
wiley   +1 more source

The effectiveness of diabetes education on the lipid profile and HbA1c in a proactive veteran population with Type 2 Diabetes Mellitus

open access: hybrid, 2007
Megan Richardson   +5 more
openalex   +1 more source

Changes in weight and glycemic control following obesity treatment with semaglutide or tirzepatide by discontinuation status

open access: yesObesity, EarlyView.
Abstract Objective The objective of this study was to characterize changes in body weight and glycated hemoglobin (in those with prediabetes at baseline) through 12 months by obesity pharmacotherapy discontinuation status. Methods This retrospective cohort study used electronic health record data from a large health system in Ohio and Florida to ...
Hamlet Gasoyan   +8 more
wiley   +1 more source

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

open access: yesThe Journal of Pathology, EarlyView.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk   +5 more
wiley   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina   +2 more
wiley   +1 more source

Evaluation of Four Semi‐Mechanistic Models for Predicting Glycemic Control With a Glucagon Receptor Antagonist in People With Type 2 Diabetes

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Glycated hemoglobin (HbA1c) is the gold standard for measuring long‐term glycemic efficacy over at least 3 months in Type 2 diabetes (T2D). Being able to predict HbA1c using glucose response from studies of less than 3 months would be useful.
Austin Yue Feng Tan   +4 more
wiley   +1 more source

A New Classification System for Fatty Liver—What Sonographers Should Know

open access: yesSonography, EarlyView.
ABSTRACT Hepatic steatosis or fatty liver disease is a rapidly emerging health issue and is closely linked to an increase in cardiometabolic conditions such as obesity and type 2 diabetes. The nomenclature surrounding fatty liver has recently undergone multiple reviews to better reflect its underlying causes.
Elspeth L. Keys   +4 more
wiley   +1 more source

Multimodal Prehabilitation for Colorectal Cancer Patients: Study Protocol of a Nationwide Multicentre Study With Uniform Prehabilitation Protocols

open access: yesWorld Journal of Surgery, EarlyView.
The aim of prehabilitation is to optimize patient specific modifiable risk factors before major surgery, in order to enhance the individual resilience. Due to the lack of universal guidelines, prehabilitation has been conducted in various ways, making it difficult to estimate its effect.
C. R. Sabajo   +5 more
wiley   +1 more source

Towards the Development of a Conceptual Framework of the Determinants of Pre‐eclampsia: A Hierarchical Systematic Review of Biomarkers

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pre‐eclampsia is a leading cause of maternal and perinatal morbidity and mortality. There are several determinants of individual pregnant women's risk of developing pre‐eclampsia, including biomarkers and ultrasound markers. Objective A conceptual framework to collate and summarise the extensive body of literature on biomarkers ...
Terteel Elawad   +89 more
wiley   +1 more source

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