Results 281 to 290 of about 416,102 (337)

A Randomized, Double‐Blind, Placebo‐Controlled Pilot Trial With Open‐Label Extension of Sirona, a Hydrogel for Weight Loss

Obesity, EarlyView.
ABSTRACT Objective This study investigated the safety, tolerability, and preliminary efficacy of Sirona, a novel gastro‐retentive, dual‐network polymer for weight management. Methods This pilot trial comprised a randomized, parallel‐group, double‐blind, placebo‐controlled (3:1 ratio), 12‐week period, with a 12‐week open‐label extension (OLE), in ...
James P. Byrne, Elanor C. Hinton, Asif Malik Humayun, Dimitri J. Pournaras, Rebecca L. Elsworth, Jeffrey M. Brunstrom, Julian P. Hamilton‐Shield, Mark Sumeray, Camilla Easter, Hutan Ashrafian   +9 more
wiley   +1 more source

Glycated Albumin Percentage is Correlated With HbA1c: Theoretic Marker in Patients With Altered Erythrocyte Turnover. [PDF]

J Diabetes Sci Technol
Gåfvels M, Swärd P, Xu N, Svensson J.
europepmc   +1 more source

Impact of Glycemic Variability on Chromatin Remodeling, Oxidative Stress, and Endothelial Dysfunction in Patients With Type 2 Diabetes and With Target HbA1c Levels

Diabetes, 2017
S. Costantino, F. Paneni, R. Battista, L. Castello, G. Capretti, S. Chiandotto, L. Tanese, G. Russo, D. Pitocco, G. Lanza, M. Volpe, T. Lüscher, F. Cosentino   +12 more
semanticscholar   +1 more source

People With Lowest Physical Functioning Scores Showed Greatest Improvement After Tirzepatide Treatment

Obesity, EarlyView.
ABSTRACT Objective This post hoc analysis of SURMOUNT trials assessed the association of baseline physical function (PF) with obesity‐related complications (ORCs), efficacy measures, and PF. The mechanism of tirzepatide‐led improvements in PF was evaluated. Methods Outcomes were assessed among participants (SURMOUNT‐1 = 2539; SURMOUNT‐3 = 579; SURMOUNT‐
Xuan Li, Dachuang Cao, Helene Sapin, Fangyu Wang, Theresa Hunter Gibble, Nedina Kalezic Raibulet, Max Denning, Lee M. Kaplan   +7 more
wiley   +1 more source

Immunomodulatory interventions in type 1 diabetes: a systematic review and meta-analysis revealing paradoxical dissociation between beta-cell preservation and glycemic control. [PDF]

BMC Endocr Disord
Biswas S, Dhir B, Talasila S, Namala S, Kimmatkar A, Bhamidi N, Ezhil SR, Safa UB, Reza IMK, Sribhashyam VP, Srivastava Y, Bharia U, Mohammad S, Jaswal A, Abedin ZU, Kumar V, Singh S, Haward R.   +17 more
europepmc   +1 more source

Hemoglobin A1c (HbA1c) changes over time among adolescent and young adult participants in the T1D exchange clinic registry

Pediatric Diabetes, 2016
M. Clements, N. Foster, D. Maahs, D. Schatz, B. Olson, E. Tsalikian, Joyce M Lee, C. Burt‐Solorzano, W. Tamborlane, V. Chen, K. Miller, R. Beck   +11 more
semanticscholar   +1 more source

Application of the Lancet Commission Criteria for the Diagnosis of Obesity to a Clinical Trials Population: The LEAP Trial

Obesity, EarlyView.
ABSTRACT Objective This study aimed to apply The Lancet Diabetes & Endocrinology criteria for diagnosing obesity among clinical trial participants and understand participants' characteristics by obesity status. Methods The criteria were operationalized and applied to baseline data from the Long‐term Effectiveness of the Anti‐obesity medication ...
Faith Anne N. Heeren, Kathleen R. Ruddiman, Courtney Simmons, Brian N. White, Byron C. Jaeger, Nicholas M. Pajewski, Stephanie A. Hooker, Deborah B. Horn, Katy Martin‐Fernandez, Kimberly A. Gudzune, Caroline Blackwell Young, Jamy Ard, Kristina Henderson Lewis   +12 more
wiley   +1 more source

The association between glycated hemoglobin and intraocular inflammatory factors in patients with proliferative diabetic retinopathy. [PDF]

Int J Retina Vitreous
Liu J, Yu M, Yan J, Chen W, Zhang P, Wang Y, Chen H, Hu J.   +7 more
europepmc   +1 more source

Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP‐1 Receptor Agonists: A Network Meta‐Analysis of Randomized Controlled Trials

Obesity, EarlyView.
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella, Patricia M. Ortega, Víctor Valentí Azcárate, Fernando Rotellar Sastre, Adriana Uriz Pagola, Ahmed Ahmed, Sanjay Purkayastha, Carlota Tuero Ojanguren, Nuria Blanco Asensio, Manuel F. Landecho   +9 more
wiley   +1 more source

Age-related variations in HbA1c improvements: insights from a telehealth-supported community-based intervention. [PDF]

Innov Aging
Porterfield L, Yu X, Amspoker AB, Johnston CA, Naik AD, Virani SS, Ballantyne CM, Balasubramanyam A, Vaughan EM.   +8 more
europepmc   +1 more source