Results 31 to 40 of about 416,102 (337)

Effect of Iron Deficiency on Glycation of Haemoglobin in Nondiabetics [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Protein glycation is a spontaneous reaction that is believed to play a key role in the pathogenesis of many clinical disorders. The glycation of proteins is enhanced by elevated glucose concentrations.
Balasubramanian Shanthi, Carnagarin Revathy, Arcot Jagdeeshwaran Manjula Devi, Subhashree   +3 more
doaj   +1 more source

Significance of HbA1c Test in Diagnosis and Prognosis of Diabetic Patients

Biomarker Insights, 2016
Diabetes is a global endemic with rapidly increasing prevalence in both developing and developed countries. The American Diabetes Association has recommended glycated hemoglobin (HbA1c) as a possible substitute to fasting blood glucose for diagnosis of ...
Shariq I. Sherwani, H. Khan, Aishah A. Ekhzaimy, A. Masood, M. Sakharkar   +4 more
semanticscholar   +1 more source

Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]

, 2015
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst, Cavalot, Chun Shing Kwok, Evangelos Kontopantelis, Foo, Grant Heatlie, Hermann, Iain Buchan, Kontopantelis, Lin, Maciejewski, Mamas A. Mamas, Martin K. Rutter, Phyo K. Myint, Raman, Saadia Aslam, Skriver, Sperrin, Yoon Loke   +18 more
core   +1 more source

The Relationships Between Time in Range, Hyperglycemia Metrics, and HbA1c

Journal of Diabetes Science and Technology, 2019
Background: As the use of continuous glucose monitoring (CGM) increases, there is a need to better understand key metrics of time in range 70-180 mg/dL (TIR70-180) and hyperglycemia and how they relate to hemoglobin A1c (A1C).
R. Beck, R. Bergenstal, P. Cheng, C. Kollman, Anders L. Carlson, Mary L. Johnson, D. Rodbard   +6 more
semanticscholar   +1 more source

HbA1c Levels in Type 1 Diabetes from Early Childhood to Older Adults: A Deeper Dive into the Influence of Technology and Socioeconomic Status on HbA1c in the T1D Exchange Clinic Registry Findings

Diabetes Technology & Therapeutics, 2020
Objective: The T1D Exchange Clinic Registry figure of HbA1c levels according to age has become a classic picture of how average HbA1c varies from childhood to elderly.
K. Miller, R. Beck, N. Foster, D. Maahs
semanticscholar   +1 more source

Common Variants at 10 Genomic Loci Influence Hemoglobin A(1C) Levels via Glycemic and Nonglycemic Pathways [PDF]

, 2010
OBJECTIVE Glycated hemoglobin (HbA1c), used to monitor and diagnose diabetes, is influenced by average glycemia over a 2- to 3-month period. Genetic factors affecting expression, turnover, and abnormal glycation of hemoglobin could also be associated ...
Abecasis, G, Altshuler, D, Arking, D, Balkau, B, Barnes, D, Barroso, I, Boehnke, M, Boerwinkle, E, Bohm, B, Boinstein, SR, Bonnefond, A, Bonnycastle, LL, Boomsma, DI, Bottcher, Y, Bouatia-Naji, N, Bumpstead, S, Burnett-Miller, MS, Campbell, H, Cao, A, Chambers, J, Clark, R, Collins, FS, Coresh, J, de Geus, EJC, Dei, M, Deloukas, P, Devaney, JM, Doring, A, Dupuis, J, Egan, JM, Elosua, R, Epstein, SE, Erdmann, J, Ferrucci, L, Fleming, MD, Florez, JC, Forouhi, N, Fox, CS, Franklin, C, Franzosi, MG, Froguel, P, Gallina, S, Gieger, C, Goe, A, Graessler, J, Grallert, H, Greinacher, A, Groop, L, Hadley, D, Hakonarson, HH, Hall, A, Hamsten, A, Hayward, C, Heath, S, Heeney, MM, Herder, C, Homuth, G, Hottenga, JJ, Hunter-Merrill, R, Illig, T, Jackson, AU, Jula, A, Kao, WHL, Kathiresan, S, Khaw, KT, Kleber, M, Knouff, CW, Kong, A, Kooner, J, Kottgen, A, Kovacs, P, Krohn, K, Kuhne, B, Kuusisto, J, Laakso, M, Langenberg, C, Lathrop, M, Lecoeur, C, Li, M, Li, MY, Loos, RJF, Luan, JA, Lyssenko, V, Magi, R, Magnusson, PKE, Malarstig, A, Mangino, M, Martinez-Larrad, MT, Marz, W, McArdle, WL, McCarthy, MI, McPherson, R, Meigs, JB, Meisinger, C, Meitinger, T, Melander, O, Mohlke, KL, Mooser, VE, Morken, MA, Narisu, N, Nathan, DM, Nauck, M, O'Donne, C, Oexle, K, Olla, N, Pankow, JS, Payne, F, Peden, JF, Pedersen, NL, Peltonen, L, Perola, M, Polasek, O, Porcu, E, Procardis Consortium,, Prokopenko, I, Rader, DJ, Radke, D, Rathmann, W, Reilly, MP, Ricketts, SL, Ripatti, S, Roberts, R, Rocheleau, G, Roden, M, Rudan, I, Salomaa, V, Samani, NJ, Sandhu, MS, Sanna, S, Saxena, R, Schlessinger, D, Schunkert, H, Schwarz, P, Seedorf, U, Selvin, E, Serrano-Rios, M, Shrader, P, Silveira, A, Siscovick, D, Sladek, R, Song, K, Soranzo, N, Spector, TD, Stefansson, K, Steinthorsdottir, V, Stewart, AFR, Stolerman, E, Strachan, DP, Strawbridge, R, Stumvoll, M, Surakka, I, Swift, AJ, Tanaka, T, Teumer, A, Thorleifsson, G, Thorsteinsdottir, U, Tonjes, A, Uda, M, Usalai, G, Vitart, V, Voight, BF, Volzke, H, Wallaschofski, H, Wareham, NJ, Waterworth, DM, Watkins, H, Wheeler, E, Wichmann, HE, Wild, SH, Willemsen, G, Willenborg, C, Williams, GH, Wilson, JF, Winkelmann, J, Wright, AF, Wright, B, WTCCC,, Zabena, C, Zhao, JH   +178 more
core   +8 more sources

Validation and determination of a reference interval for Canine HbA1c using an immunoturbidimetric assay [PDF]

, 2017
Background: Hemoglobin A1c (HbA1c) provides a reliable measure of glycemic control over 2–3 months in human diabetes mellitus. In dogs, presence of HbA1c has been demonstrated, but there are no validated commercial assays. Objective: The purpose
Goemans, Anne F., Ramsey, Ian K., Spence, Susanna J.   +2 more
core   +1 more source

Add-on therapy of herbal formulation rich in standardized fenugreek seed extract in type 2 diabetes mellitus patients with insulin therapy: An efficacy and safety study

Asian Pacific Journal of Tropical Biomedicine, 2018
Objective: To assess the safety and efficacy of herbal formulation rich in standardized fenugreek seed extract (IND-2) add-on therapy in type 2 diabetes mellitus (T2DM) patients who were on insulin treatment in prospective, single arm, open-label ...
Amit Kandhare, Uday Phadke, Abhay Mane, Prasad Thakurdesai, Sunil Bhaskaran   +4 more
doaj   +1 more source

In vitro determination of hemoglobin A1c for diabetes diagnosis and management: technology update [PDF]

, 2014
It is fascinating to consider the analytical improvements that have occurred since glycated hemoglobin was first used in routine clinical laboratories for diabetes monitoring around 1977; at that time methods displayed poor precision, there were no ...
English, Emma, John, W Garry, Milosevich, Elise T   +2 more
core   +1 more source

A greater proportion of participants with type 2 diabetes achieve treatment targets with insulin degludec/liraglutide versus insulin glargine 100 units/mL at 26 weeks. DUAL VIII, a randomized trial designed to resemble clinical practice [PDF]

, 2020
This report presents the efficacy and safety of insulin degludec/liraglutide (IDegLira) versus insulin glargine 100 units/mL (IGlar U100) as initial injectable therapy at 26 weeks in the 104-week DUAL VIII durability trial (NCT02501161). Participants (N =
Aroda, V. R., Bardtrum, L., Dagdelen, S., Halladin, N., Haluzik, M., Orsy, P., Rodriguez, M., Sesti, G.   +7 more
core   +1 more source