Results 81 to 90 of about 416,102 (337)

High serum osteopontin levels are associated with prevalent fractures and worse lipid profile in post-menopausal women with type 2 diabetes [PDF]

, 2018
Purpose: Patients with type 2 diabetes (T2DM) have increased fracture risk. Osteopontin (OPN) is a protein involved in bone remodeling and inflammation.
Carnevale, V., Filardi, Tiziana, Lenzi, A., Massoud, R., Morano, S., Nieddu, L., Romagnoli, E., Russo, C., Tavaglione, F., Turinese, Irene   +9 more
core   +1 more source

The Fallacy of Average: How Using HbA1c Alone to Assess Glycemic Control Can Be Misleading

Diabetes Care, 2017
HbA1c is a valuable metric for comparing treatment groups in a randomized trial, for assessing glycemic trends in a population over time, or for cross-sectional comparisons of glycemic control in different populations.
R. Beck, Crystal G. Connor, Deborah M. Mullen, D. Wesley, R. Bergenstal   +4 more
semanticscholar   +1 more source

The Effect of Anemia and the Goal of Optimal HbA1c Control in Diabetes and Non-Diabetes

Cureus, 2020
Hemoglobin A1c (HbA1c) is the gold standard for the diagnosis of diabetes; however, many clinical conditions affect the HbA1c level, including anemia. And, the most common causes of anemia worldwide include iron deficiency anemia (IDA).
Prakash C Katwal, Srood Jirjees, Z. Htun, Israa Aldawudi, Safeera Khan   +4 more
semanticscholar   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

Definition of the upper reference limit of glycated albumin in blood donors from Italy [PDF]

, 2017
Glycated Albumin (GA) has been proposed as a short-term indicator of glycemic homeostasis. The aim of this study is to describe the distribution of GA in a large sample of blood donors from Italy to evaluate whether demographic features, namely age and ...
Agnello, Luisa, Bellia, Chiara, Bivona, Giulia, Ciaccio, Marcello, Cosma, Chiara, Plebani, Mario, Sasso, Bruna Lo, Zaninotto, Martina   +7 more
core   +1 more source

Visit-to-Visit HbA1c Variability Is Associated With Cardiovascular Disease and Microvascular Complications in Patients With Newly Diagnosed Type 2 Diabetes

Diabetes Care, 2019
OBJECTIVE To investigate the association between visit-to-visit HbA1c variability and cardiovascular events and microvascular complications in patients with newly diagnosed type 2 diabetes.
Sheyu Li, Imola Németh, L. Donnelly, Simona Hapca, K. Zhou, E. Pearson   +5 more
semanticscholar   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Discriminating Low to High Adherent Type 2 Patients with Diabetes by Glycosylated Hemoglobin A1c, Eating Self-Efficacy and Other Psychosocial Determinants: Difference Between Patient and Physician Adherence Models

Patient Preference and Adherence, 2022
Tamás Köbling,1 Éva Katona,1 László Maroda,2 Zita Váradi,1 Sándor Somodi,3 Dénes Páll,1,2 Miklós Zrínyi2 1Department of Medicine, University of Debrecen, Debrecen, Hungary; 2Coordination Center for Drug Development, University of Debrecen, Debrecen ...
Köbling T, Katona É, Maroda L, Váradi Z, Somodi S, Páll D, Zrínyi M   +6 more
doaj  

Exposure to Household Air Pollution from Biomass-Burning Cookstoves and HbA1c and Diabetic Status Among Honduran Women [PDF]

, 2018
Household air pollution from biomass cookstoves is estimated to be responsible for more than two and a half million premature deaths annually, primarily in low and middle‐income countries where cardiometabolic disorders, such as Type II Diabetes, are ...
Africano, S., Bachand, A. M., Benka-Coker, Megan L., Brook, R. D., Clark, M. L., Good, N., Koehler, K., L\u27Orange, C., Nelson, T. L., Osorto Pinel, A. B., Peel, J. L., Rajkumar, S., Reynolds, S. J., Volckens, J., Young, B. N.   +14 more
core   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source