Results 171 to 180 of about 93,843 (327)

IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AAV-HBV mouse model. [PDF]

open access: yesFront Immunol
Lewis G   +7 more
europepmc   +1 more source

The Antiviral Activity of Polyphenols

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard   +5 more
wiley   +1 more source

Genetic alterations in hepatocellular carcinoma after sustained virological response in relation to the molecular characterization of metabolic diseases

open access: yesHepatology Research, Volume 55, Issue 8, Page 1193-1203, August 2025.
Hepatocellular carcinoma (HCC) in the hepatitis C virus (HCV)‐sustained virologic response (SVR) group was associated with alcohol consumption and metabolic diseases and showed significantly lower rates of ARID2 alterations and AXIN1 alterations compared to the HCV‐non‐SVR group, with a mutational profile resembling that of the steatotic liver disease ...
Fukiko Kawai‐Kitahata   +21 more
wiley   +1 more source

A potent GalNAc-siRNA drug, RBD1016, leads to sustained HBsAg reduction and seroconversion in mouse models of HBV infection. [PDF]

open access: yesMol Ther Nucleic Acids
Zheng S   +9 more
europepmc   +1 more source

Predicting the risk of developing diabetes in steatotic liver disease using controlled attenuation parameter in a health checkup population

open access: yesHepatology Research, Volume 55, Issue 8, Page 1101-1110, August 2025.
Higher amounts of liver fat, measured noninvasively using the controlled attenuation parameter (CAP), are a strong predictor of the future development of type 2 diabetes mellitus. The risk increases in proportion to the increase in CAP. Measuring CAP could help identify individuals who need diabetes prevention strategies.
Takuma Nakatsuka   +22 more
wiley   +1 more source

Correction: Pre-activation of toll-like receptor 2 enhances CD8+ T-cell responses and accelerates hepatitis B virus clearance in the mouse models. [PDF]

open access: yesFront Immunol
Lin Y   +14 more
europepmc   +1 more source

Duration of Nucleos(t)ide Analogue Treatments in Patients With Chronic Hepatitis B Virus Infection in the United States

open access: yesJournal of Viral Hepatitis, Volume 32, Issue 8, August 2025.
ABSTRACT Viral hepatitis caused by hepatitis B virus accounts for a significant disease burden. Nucleos(t)ide analogues (NAs) are the standard of care for chronic hepatitis B (CHB) infection; however, treatment is long‐term, and viral eradication resulting in cure is rare. Adherence to NAs is vital for disease control.
Seth Anderson   +9 more
wiley   +1 more source

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