Results 171 to 180 of about 136,614 (358)

Landscape of Somatic and Age‐Related Pathogenic Structural Variations in Hepatocellular Carcinoma Revealed by Long‐Read Sequencing

MedComm, Volume 7, Issue 1, January 2026.
This study leveraged long‐read sequencing (LRS) to provide a comprehensive analysis of structural variations (SVs) in the human hepatocellular carcinoma (HCC) genome. Somatic SVs were found to be more prevalent in HBV‐related HCC, with chromosome 1 emerging as the primary hotspot for these alterations. Notably, HBV‐related HCC exhibited a significantly
Zhewen Wei, Yinghao Cao, Hongchao Liu, Mei Liu, Bolun Zhang, Jianming Ying, Jianqiang Cai, Xinyu Bi, Jianjun Zhao, Jianguo Zhou, Zhiyu Li, Zhen Huang, Jianmei Liu, Xueyan Lv, Zhiwen Luo, Zhicheng Wei, Xiaoshi Zhang, Yi Yang, Yiqiao Deng, Yanjiang Yin, Jinghua Chen, Junbo Liang, Xiaoyue Wang, Yefan Zhang, Hong Zhao   +24 more
wiley   +1 more source

Assessment of Occupational Exposure to Blood and Other Body Fluids Among Healthcare Workers in a South‐Western Chinese Tertiary Hospital From 2018 to 2023: A Descriptive Cross‐Sectional Study

Nursing Open, Volume 13, Issue 1, January 2026.
ABSTRACT Aim Healthcare workers face significant occupational exposure risks from biological and non‐biological hazards, with needlestick injuries being the most common hazard. This study aimed to assess the extent of occupational exposure among various healthcare workers. Design A descriptive cross‐sectional study.
Lulin Chen, Wei Liu, Chunting Dong, Jun Yang, Yongjiang Gan, Yao Zhong, Danyan Liang   +6 more
wiley   +1 more source

Preliminary assessment of various additives on the specific reactivity of anti- rHBsAg monoclonal antibodies [PDF]

, 2015
Background: Antibodies have a wide application in diagnosis and treatment. In order to maintain optimal stability of various functional parts of antibodies such as antigen binding sites, several approaches have been suggested.
Mohammadi, S., Shokri, F., Yazdani, Y., Yousefi, M.   +3 more
core  

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, Volume 10, Issue 2, 22 January 2026.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Low prevalence of hepatitis B and C among tuberculosis patients in Duhok Province, Kurdistan: Are HBsAg and anti-HCV prerequisite screening parameters in tuberculosis control program?

, 2016
Muayad Aghali Merza, Safer M. Haji, Abid Mohialdeen Hasan Alsharafani, Shivan U. Muhammed   +3 more
openalex   +1 more source

Low hepatitis B surface antigen at baseline and increased ALT levels during treatment predicts significant HBsAg decline in peginterferon alfa added to long-term nucleus(t)ice analogue. Results from two randomized controlled trials in 165 patients

, 2020
Mina Farag, Hannah Choi, Scott Fung, Heng Chi, Margo J. H. van Campenhout, Seng Liem, Qing Xie, Milan J. Sonneveld, David Wong, Jordan J. Feld, Karel J. van Erpecum, Robert de Man, Bettina E. Hansen, Harry L.A. Janssen   +13 more
openalex   +1 more source

STUDY OF rs1059513 STAT6 POLYMORPHISM IN HBsAg(+) HEPATOCELLULAR CARCINOMA PATIENTS

, 2023
Quang Nhựt Lê, Quang Huy Dương, Xuân Kiên Nguyễn   +2 more
openalex   +2 more sources

Efficacy and Safety of Tenofovir Alafenamide (TAF) and Tenofovir Disoproxil Fumarate (TDF) Followed by TAF in Chronic Hepatitis B Patients of East Asian Ethnicity Following 5 Years of Treatment

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 1, Page 132-144, January 2026.
In East Asian patients with chronic hepatitis B, rates of virologic suppression through 5 years were high in those treated continuously with tenofovir alafenamide (TAF) and in those switched from tenofovir disoproxil fumarate (TDF) to TAF. Improved renal and bone safety was observed in patients switching from TDF to TAF.
Grace Lai‐Hung Wong, Edward Gane, Calvin Q. Pan, Scott Fung, Mang M. Ma, Namiki Izumi, Shalimar, Seng Gee Lim, Wan‐Long Chuang, Rajiv Mehta, Young‐Suk Lim, Leland J. Yee, John F. Flaherty, Frida Abramov, Hongyuan Wang, Maria Buti   +15 more
wiley   +1 more source

Long‐Term Follow‐Up of Patients in a Prospective Study of NA Discontinuation Identifies Different Patterns of HBsAg Loss

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 2, Page 231-241, January 2026.
We evaluated long‐term outcomes following nucleos(t)ide analogue discontinuation in HBeAg‐negative chronic hepatitis B. HBsAg loss was infrequent. Early HBsAg loss occurred in patients with low end‐of‐treatment HBsAg levels and without ALT flare, whilst late HBsAg loss typically followed ALT flares and was associated with higher end‐of‐treatment HBsAg ...
Simon J. Hume, Samuel Hall, Gareth Burns, Sara Vogrin, Daniel Tassone, Paul Desmond, Dilip Ratnam, Miriam T. Levy, Rohit Sawhney, Amanda Nicoll, Zina Valaydon, Simone I. Strasser, Meng Ngu, Marie Sinclair, Chris Meredith, Gayle V. Matthews, Kumar Visvanathan, Jacinta A. Holmes, Alexander J. Thompson   +18 more
wiley   +1 more source

A simple-to-use score system for predicting HBsAg clearance to peginterferon alfa-2b in nucleoside analogs-experienced chronic hepatitis B patients [PDF]

, 2023
Kaimin Song, Da‐Wu Zeng, Yijuan Zheng, Huatang Zhang, Zhangyan Weng, Yongjun Zhou, Zhijun Su, Xueping Yu   +7 more
openalex   +1 more source