Results 281 to 290 of about 136,614 (358)

RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

Science Translational Medicine, 2017
Christine I Wooddell, Man-Fung Yuen, Henry Lik Yuen Chan   +2 more
exaly   +2 more sources

Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance We detected cfDNA somatic mutations in combination with protein markers to efficiently identify early stage HCC from asymptomatic HBsAg-seropositive individuals in a community population.
Chunfeng Qu, Yuting Wang, Kun Chen
exaly   +2 more sources

Global epidemiology of hepatitis B virus infection: New estimates of age-specific HBsAg seroprevalence and endemicity

Vaccine, 2012
J. J. Ott, Gretchen A. Stevens, J. Groeger, S. Wiersma   +3 more
exaly   +2 more sources

Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice

Nature Communications, 2019
Hepatitis B virus (HBV) can induce chronic inflammation, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite evidence suggesting a link between adaptive immunity and HBV-related diseases in humans, the immunopathogenic mechanisms involved ...
Hui Peng, Cheng Sun, Yongyan Chen
exaly   +2 more sources

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Association between fatty liver and cirrhosis, hepatocellular carcinoma, and HBsAg seroclearance in chronic hepatitis B.

Journal of Infectious Diseases, 2020
BACKGROUND Chronic hepatitis B (CHB) and fatty liver (FL) are common, natural history data on concurrent FL and CHB (FL-CHB) are limited. This study aimed to evaluate the effect of FL on cirrhosis, hepatocellular carcinoma (HCC), and HBsAg seroclearance ...
Jie Li, Hwai I. Yang, M. Yeh, M. Le, A. Le, Y. Yeo, C. Dai, Scott D Barnett, Jian Q. Zhang, Jee‐Fu Huang, H. Trinh, C. Wong, Clifford Wong, J. Hoang, R. Cheung, Ming‐Lung Yu, M. Nguyen   +16 more
semanticscholar   +1 more source

Discontinuation of nucleos(t)ide analogues is not associated with a higher risk of HBsAg seroreversion after antiviral-induced HBsAg seroclearance: a nationwide multicentre study

Gut, 2020
Objective Direct comparison of the clinical outcomes between nucleos(t)ide analogue (NA) discontinuation versus NA continuation has not been performed in patients with chronic hepatitis B who achieved HBsAg-seroclearance.
M. A. Kim, Seung Up Kim, D. Sinn, Jeong Won Jang, Y. Lim, S. Ahn, Jae-Jun Shim, Y. Seo, Y. Baek, Sang Gyune Kim, Young Seok Kim, J. H. Kim, W. Choe, H. Yim, Hyun Woong Lee, J. Kwon, S. Lee, J. Jang, Hwi-Young Kim, Yewan Park, Gi-Ae Kim, Hyun Yang, Han Ah Lee, Myeongseok Koh, Young-Sun Lee, Minkoo Kim, Young Chang, Y. Kim, Jung‐Hwan Yoon, F. Zoulim, Jeong‐Hoon Lee   +30 more
semanticscholar   +1 more source

Anti-HBe and Subtypes of HBsAg among Asymptomatic HBsAg Carriers

Vox Sanguinis, 1979
Abstract. Finnish HBsAg positive blood donors were analyzed for the HBsAg subtype distribution and the presence of e antigen (HBeAg) and antibody to e (anti‐HBe). 88% (159 of 180) of the donors had subtype ad and 12% (21 of 180) had ay. HBeAg was found in 1% (2 of 180) and anti‐HBe in 74% (133 of 180) of the donors.
P, Ukkonen, V, Koistinen, K, Penttinen
openaire   +2 more sources

Kidney Transplantation from HBsAg+ Living Donors to HBsAg- Recipients: Clinical Outcomes at a High-volume Center in China.

Clinical Infectious Diseases, 2020
BACKGROUND Data on kidney transplantation (KTx) from hepatitis B surface antigen (HBsAg)+ donors to HBsAg- recipients [D(HBsAg+)/R(HBsAg-)] are limited. We aimed to report the outcomes of D(HBsAg+)/R(HBsAg-) KTx in recipients with or without hepatitis B ...
Xianding Wang, Jin-peng Liu, T. Song, Zhong-li Huang, Yu Fan, Yunying Shi, Li-yu Chen, Y. Lv, Zilin Xu, Xiao-hong Li, Li Wang, Tao Lin   +11 more
semanticscholar   +1 more source