Alimentary Pharmacology &Therapeutics, EarlyView.Statin therapy in cirrhosis may confer a survival benefit while reducing the risk of hepatic decompensation and hepatocellular carcinoma. ABSTRACT Background The role of statins in cirrhosis remains controversial. Historically restricted due to safety concerns, emerging evidence highlights potential pleiotropic benefits, though effects on mortality and
Bernardo de Faria Moraes +8 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola +95 more
wiley +1 more source
Disrupting Viral Persistence: CRISPR/Cas9-Based Strategies for Hepatitis B and C Treatment, and Challenges. [PDF]
J Cell Mol MedLi MF, Zubair A, Wdidi S, He S.
europepmc +1 more source
Long-term hepatic consequences of chemotherapy-related HBV reactivation in lymphoma patients
, 2005 Wen-Pin Su
openalex +2 more sources
Phylogenetic analysis of torque teno virus genome from Pakistani isolate and incidence of co-infection among HBV/HCV infected patients [PDF]
, 2012 Tabinda Hussain +4 more
openalex +1 more source
Cancer Science, EarlyView.SPP1 was identified as a key driver of intratumoral fibrosis and hepatocellular carcinoma (HCC) progression through transcriptomic, histological, and functional analyses. Mechanistically, SPP1 promotes HSC activation and fibrosis via the SPP1–CD44–GLI1 axis, and pharmacologic inhibition of Hedgehog signaling effectively reduces tumor growth and ...
Atsushi Nara +16 more
wiley +1 more source
Haemoglobin vesicles as artificial red blood cells developed for use as a transfusion alternative: an open-label, single-centre phase Ib study protocol in Japan. [PDF]
BMJ OpenSakai K +6 more
europepmc +1 more source
PEP-Hep: A cluster randomised controlled trial of a prison education programme to improve hepatitis B and C testing uptake and treatment initiation in Ghana - A study protocol. [PDF]
BMJ OpenSenoo-Dogbey VE +8 more
europepmc +1 more source
Biologic treatments for psoriasis have different anatomical specificities in residual PASI
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and objectives Improved understanding of the immunopathogenesis of psoriasis has led to the development of effective targeted therapies, but patients who respond to treatment without total skin clearance have residual disease. The aim of this study was to demonstrate the existence of specific residual disease (or residual PASI ...
Martina Burlando +8 more
wiley +1 more source