Results 111 to 120 of about 78,362 (247)

Large Language Models in Cardiovascular Imaging: Current Applications and Future Prospects

Med Research, EarlyView.
Weifeng Yuan, Rong Xu, Shengkun Peng, Yingkun Guo   +3 more
wiley   +1 more source

An experimental approach to assess the combined effects of multiple stressors on a large vertebrate species

Conservation Biology, EarlyView.
Abstract The design of experiments to investigate the combined effects of multiple stressors requires exposing target organisms to multiple combinations of stressor doses. Concurrent manipulation of stressors is often infeasible with wildlife, but long‐lasting health effects allow individual health to be used as an integrator of prior stressor exposure.
Enrico Pirotta, Catriona M. Harris, Lori H. Schwacke, Len Thomas, Jason B. Allen, Aaron A. Barleycorn, Marco Casoli, Jonathan Crossman, Laura Aichinger Dias, Laura Engleby, Erin LaBrecque, Jenny A. Litz, Katherine A. McHugh, Patrick J. O. Miller, Michael J. Moore, Theoni Photopoulou, Brian M. Quigley, Cynthia R. Smith, Brandon L. Southall, Todd R. Speakman, Ryan Takeshita, Christina N. Toms, Randall S. Wells, Eric S. Zolman, Peter L. Tyack   +24 more
wiley   +1 more source

Development of NAFLD‐Specific Human Liver Organoid Models on a Microengineered Array Chip for Semaglutide Efficacy Evaluation

Cell Proliferation, EarlyView.
Microporous array organ chips were integrated with commercially available well plates to develop organoid chip platforms, which enable modelling of hepatic physiology and non‐alcoholic fatty liver disease (NAFLD) pathogenesis, as well as evaluation of semaglutide therapeutics. ABSTRACT Progressive non‐alcoholic fatty liver disease (NAFLD) may culminate
Xiao‐yan You, Xiang‐yang Li, Hui Wang, Guo‐ping Zhao   +3 more
wiley   +1 more source

Adjuvant therapy of severe and/or refractory bullous pemphigoid with immunoadsorption – A prospective monocenter pilot study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Bullous pemphigoid (BP) is the most common autoimmune blistering disease in the Western world. While remission is achieved in the majority of BP patients by long‐term use of corticosteroids with or without immunomodulants/immunosuppressants, national and international guidelines recommend adjuvant immunoadsorption (IA)
Maike M. Holtsche, Nina van Beek, Christoph M. Hammers, Artem Vorobyev, Michael Kasperkiewicz, Nina Schumacher, Philip Muck, Enno Schmidt   +7 more
wiley   +1 more source

Reallocating morning physical activity to later‐day activity and its association with type 2 diabetes incidence: The Maastricht Study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The timing of physical activity may influence metabolic health through interactions with circadian rhythms, yet its role in type 2 diabetes mellitus (T2DM) development is unclear. We investigated associations between time‐of‐day‐specific physical activity and incident T2DM, and whether theoretically reallocating activity from morning to ...
Marvin Y. Chong, Simone J. P. M. Eussen, Jeroen H. P. M. van der Velde, Bastiaan E. de Galan, Hans H. C. M. Savelberg, Hans Bosma, Martijn J. L. Bours, Matty P. Weijenberg, Annemarie Koster   +8 more
wiley   +1 more source

ATTR Gene Variants in HCM

JACC: Case Reports
Hypertrophic cardiomyopathy is the most common inherited cardiomyopathy, with a prevalence of 1:200 to 1:500. Cardiac amyloidosis, another cardiomyopathy caused by myocardial deposition of abnormally folded TTR protein, can be acquired or hereditary. The presence of pathogenic TTR gene variants in patients with phenotypic HCM is an underrecognized and ...
Anthony J. Kanelidis, Jeremy A. Slivnick, Rachel Campagna, Bryan Smith, Sara Kalantari, Nitasha Sarswat, Gene Kim   +6 more
openaire   +4 more sources

Physical activity and meal timing alignment with chronotype and their associations with glucose metabolism: The Maastricht Study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Little is known about how the alignment between daily behaviours, such as physical activity and eating, and chronotype relates to glucose metabolism. We investigated whether alignment of physical activity and meal timing with chronotype was associated with glycaemic parameters and with prediabetes or type 2 diabetes (T2DM).
Marvin Y. Chong, Joseph Henson, Martijn J. L. Bours, Hans Bosma, Bastiaan E. de Galan, Carla J. H. van der Kallen, Ree M. Meertens, Hans H. C. M. Savelberg, Miranda T. Schram, Matty P. Weijenberg, Thomas Yates, Annemarie Koster, Simone J. P. M. Eussen   +12 more
wiley   +1 more source

Clinical and pathophysiologic determinants of catheter ablation outcome in hypertrophic cardiomyopathy with atrial fibrillation

Journal of Arrhythmia
Background Hypertrophic cardiomyopathy (HCM) is frequently associated with atrial fibrillation (AF). We compared clinical, echocardiographic, and electrophysiological parameters between HCM subtypes and those without HCM at AF catheter ablation (AFCA ...
Jae‐Hyuk Lee, Iksung Cho, Sung Hwa Choi, Hee Tae Yu, Tae‐Hoon Kim, Jae‐Sun Uhm, Boyoung Joung, Moon‐Hyoung Lee, Geu‐Ru Hong, Chun Hwang, Hui‐Nam Pak   +10 more
doaj   +1 more source

An Open Framework for Integrating Widely Distributed Hypermedia Resources

, 1996
The success of the WWW has served as an illustration of how hypermedia functionality can enhance access to large amounts of distributed information. However, the WWW and many other distributed hypermedia systems offer very simple forms of hypermedia ...
Dale, Jonathan, DeRoure, David C., Goose, Stuart, Hall, Wendy, Hill, Gary J.   +4 more
core   +1 more source

Value of ultra‐high‐field MRI in patients with drug‐resistant focal epilepsy and negative 3T MRI (EpiUltraStudy): Diagnostic gain of 7T structural analysis

Epilepsia, EarlyView.
Abstract Objective Resective epilepsy surgery is an evidence‐based treatment option for patients with focal drug‐resistant epilepsy (DRE). Seizure outcome after surgery is largely dependent on detection and delineation of an epileptogenic lesion on magnetic resonance imaging (MRI). However, detection fails in 30% of patients at 3 Tesla (T) MRI, thereby
Rick H. G. J. van Lanen, Daniel Uher, Christianne M. C. Hoeberigs, Paul A. M. Hofman, Remco Santegoeds, Christopher Wiggins, Desmond H. Y. Tse, Esther G. M. Steijvers, Jacobus F. A. Jansen, Gerald S. Drenthen, Alard Roebroeck, Dimo Ivanov, Benedikt A. Poser, Sander M. J. van Kuijk, Govert Hoogland, Kim Rijkers, Louis G. L. Wagner, Guido Widman, Jan Beckervordersandforth, Sylvia Klinkenberg, Rob P. W. Rouhl, Daniel Delev, Hans Clusmann, Stefan Wolking, Yvonne Weber, Laurien K. Dhaenens‐Meyer, Elisabeth Schriewer, Alfred Meurs, Katrien Jansen, Tom Theys, Wim van Paesschen, Dirk van Roost, Walter H. Backes, Albert J. Colon, Olaf E. M. G. Schijns, on behalf of the ACE Epilepsy Surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen, Ilse van Straaten   +56 more
wiley   +1 more source