Towards a Quantitative Understanding of Aficamten Clinical Pharmacology: Pharmacokinetic-Cardiodynamic Modeling to Support Safety and Efficacy. [PDF]
CPT Pharmacometrics Syst PharmacolLutz JD +5 more
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Efficacy and safety of sodium-glucose cotransporter inhibitors in hypertrophic cardiomyopathy: a systematic review. [PDF]
Int J Cardiol Heart VascBianchi L +6 more
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Long-term outcomes after septal reduction therapy for obstructive hypertrophic cardiomyopathy: a nationwide cohort study. [PDF]
Eur Heart J OpenSchelldorfer A +5 more
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Machine learning-based risk stratification identifies heart failure with preserved ejection fraction as an independent predictor of adverse outcomes in hypertrophic cardiomyopathy. [PDF]
Sci RepZhang W +18 more
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The EXPLORER-HCM study: mavacamten for obstructive HCM
Video Journal of Biomedicine, 2021This video summarizes the underlying cause of hypertrophic cardiomyopathy (HCM), common symptoms of HCM, mechanism of action of mavacamten, and key results of the EXPLORER-HCM trial, which compared mavacamten to placebo in patients with obstructive HCM. The results of the EXPLORER-HCM study were recently published in the The Lancet.
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LVH (left ventricular hypertrophy) is one of the most common presentations in aortic stenosis and sometimes it would be missed to evaluate for other causes of the LVH in the presence of AS. Combination of AS and hypertrophic CMP is not common too. In this case of such combination, HCM was missed until presentation with VT and apical aneurysm.
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Comparative Evaluation of US HCM & Malaysian HCM for a Multilane Highway
International Journal of Research and Innovation in Social Science, 2023This study aims to measure the effectiveness of guidelines between US Highway Capacity Manual 2010 and Malaysian Highway Capacity Manual 2011 to evaluate the performance of multilane highway. The study was conducted based on field work by using Trax Appolyon Traffic Counter from 6 October 2016 to 10 October 2016 and the data were collected on four ...
Muhammad Akram Adnan +2 more
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Health is a hot topic on the Internet. Health websites are unique from other websites because they require a more acute awareness of ethical issues due to potential life threatening risks from misuse of information. We propose and give a high-level description of a Health Content Management System (HCMS) that addresses these issues and other functional
Hamman W. Samuel, Osmar R. Zaïane
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The HCM for perceptual image segmentation
Neurocomputing, 2008This paper presents an application of a neural network, namely the hierarchical cluster model (HCM) to intermediate-level image segmentation. The HCM forms a biological model of the brain for image region segmentation employing Gestalt rules. In particular, a three level HCM is proposed to hierarchically merge pixels into regions and methods are ...
Jonathan Randall +3 more
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Shared decision-making (SDM) between physicians and patients is a necessary element of care in hypertrophic cardiomyopathy (HCM), particularly for decisions concerning prophylactic implantable defibrillators to prevent sudden death; however, SDM has much less relevance in making eligibility versus disqualification decisions for competitive athletes ...
Barry J, Maron +2 more
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