Results 31 to 40 of about 38,621 (286)

Managing the Learning Capacity of Organizational Culture in Relation to Organizational Commitment: Methodological and Empirical Overview

open access: yesOrganizacijų Vadyba: Sisteminiai Tyrimai, 2018
The primary objective of the paper is to offer qualitative analysis based on the previous relevant theoretical and empirical work for the correlation between systematic and methodological implementation of organizational commitment throughout its ...
Nakov Leonid, Ivanovski Igor
doaj   +1 more source

Mobility Patterns Mining Algorithms with Fast Speed

open access: yesEAI Endorsed Transactions on Context-aware Systems and Applications, 2015
In recent years, mobile networks and its applications are developing rapidly. Therefore, the issue to ensure quality of service (QoS) is a key issue for the service providers.
Giang Minh Duc, Le Manh, Do Hong Tuan
doaj   +1 more source

Electrophysiological Substrate and Ablation Outcomes in Atrial Fibrillation With Hypertrophic Cardiomyopathy: A Propensity-Matched Multicenter Study. [PDF]

open access: yesJ Arrhythm
Multicentre retrospective propensity‐score‐matched cohort study (n = 286; 3 centres, Pakistan; 2015‐2023) comparing electrophysiological substrate and 12‐month ablation outcomes in patients with atrial fibrillation and hypertrophic cardiomyopathy (HCM‐AF, red) versus lone atrial fibrillation (Lone AF, green; 1:1 PSM on 14 covariates).
Abrar U   +7 more
europepmc   +2 more sources

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez   +6 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis

open access: yesPharmacogenomics and Personalized Medicine, 2021
Zetao Ma,1,2,* Xizhi Wang,1,* Qingbo Lv,1 Yingchao Gong,1 Minghong Xia,1 Lenan Zhuang,1 Xue Lu,1 Ying Yang,1 Wenbin Zhang,1 Guosheng Fu,1 Yang Ye,1 Dongwu Lai1 1Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang ...
Ma Z   +11 more
doaj  

Cloud-Native HCM: Redefining Workforce Management for a Distributed Workforce [PDF]

open access: yes, 2018
The shift toward remote and hybrid work models has significantly transformed how organizations manage their workforce. As businesses adapt to this new landscape, the need for innovative solutions to manage human capital effectively has never been more ...
Nomvula, Khumalo, Dr. Thabo, Nkosi
core  

vanrooij-lab/scRNAseq-HCM-human: v 1.0

open access: yes, 2022
This version of the scripts was used to analyse the data for the publication "Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy" by Wehrens et al. published in Cell Reports (2022)
Martijn Wehrens
core   +1 more source

Evolving mortality and clinical scenarios in HCM: Where are we? [PDF]

open access: yes, 2023
Hypertrophic cardiomyopathy (HCM) is a quite common genetic heart disease with a prevalence of 1:500 in the general population. It has been 65 years since the disease was first described, and tremendous progress has been made in understanding the natural
Folgheraiter, Alessandro   +5 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma   +12 more
wiley   +1 more source

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