Results 1 to 10 of about 2,181 (197)
Direct actions of dapagliflozin and interactions with LCZ696 and spironolactone on cardiac fibroblasts of patients with heart failure and reduced ejection fraction [PDF]
ESC Heart Failure, 2023 Aims Inhibitors of SGLT2 (SGLT2i) have shown a positive impact in patients with chronic heart failure and reduced ejection fraction (HFrEF). Nonetheless, the direct effects of SGLT2i on cardiac cells and how their association with main drugs used for ...
Luis Ortega‐Paz +11 more
doaj +3 more sources
Safety of Normothermic Cardiopulmonary Bypass in Pediatric Cardiac Surgery: A System Review and Meta-Analysis [PDF]
Frontiers in Pediatrics, 2021 Objectives: Hypothermic cardiopulmonary bypass (HCPB) has been used successfully in cardiac surgery for more than half a century, although adverse effects have been reported with its use.
Tao Xiong +12 more
doaj +2 more sources
APPLICATION OF SUPERMC3.2 TO PRELIMINARY NEUTRONICS ANALYSIS FOR EUROPEAN HCPB DEMO [PDF]
EPJ Web of Conferences, 2021 In the D-T fueled tokamak, the neutrons not only carry the approximately 80% energy released in the per fusion reaction, but also are the source of radioactivity in the fusion system.
Li Bin +5 more
doaj +4 more sources
Human PD-1hiCD8+ T Cells Are a Cellular Source of IL-21 in Rheumatoid Arthritis [PDF]
Frontiers in Immunology, 2021 BackgroundRheumatoid arthritis (RA) is a prototypical autoantibody-driven autoimmune disease in which T-B interactions play a critical role. Recent comprehensive analysis suggests that PD-1+CD8+ T cells as well as two distinct IL-21-producing PD-1+CD4+ T
Kazuhiko Higashioka +12 more
doaj +2 more sources
CqsA/LuxS-HapR Quorum sensing circuit modulates type VI secretion system VflT6SS2 in Vibrio fluvialis [PDF]
Emerging Microbes and Infections, 2021 Vibrio fluvialis is an emerging enteric pathogen of increasing public health threat. Two quorum sensing (QS) systems, VfqI-VfqR and CqsA/LuxS-HapR, and two type VI secretion systems (T6SSs), VflT6SS1 and VflT6SS2, have been identified in V.
Xiaoshu Liu +8 more
doaj +2 more sources
BENCHMARKING OF THE SERPENT 2 MONTE CARLO CODE FOR FUSION NEUTRONICS APPLICATIONS [PDF]
EPJ Web of Conferences, 2021 Analyses of radiation fields resulting from a deuterium-tritium (DT) plasma in fusion devices is a critical input to the design and validation of many aspects of the reactor design, including, shielding, material lifetime and remote maintenance ...
Valentine A. +3 more
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Energies, 2023 Significant design efforts were undertaken during the Pre-Concept Design (PCD) phase of the European DEMO program to optimize the helium cooled pebble bed (HCPB) breeding blanket.
Guangming Zhou +6 more
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R&D Needs for the Design of the EU-DEMO HCPB ICD Balance of Plant in FP9
Journal of Nuclear Engineering, 2022 During the Pre-Conceptual Design Phase of the EU-DEMO, two BOP solutions for WCLL and HCPB were elaborated, as close as possible to industrial standards.
Sara Perez-Martin +3 more
doaj +1 more source
Energies, 2021 Extensive modeling and analytical work has been carried out considering the Helium-Cooled Pebble Bed Breeding Blanket (HCPB BB) Balance Of Plant (BOP) configuration of the Demonstration Power Plant (DEMO) using the Apros system code, developed by VTT ...
Marton Szogradi, Sixten Norrman
doaj +1 more source
Journal of Nuclear Engineering, 2022 The fusion program in the Karlsruhe Institute of Technology (KIT) leads the R&D of the DEMO helium-cooled pebble bed (HCPB) breeding blanket within the work package breeding blanket (WPBB) of the Eurofusion Consortium in the European Union (EU).
Ali Abou-Sena +6 more
doaj +1 more source