Addiction, EarlyView.Abstract Background and aims Injection‐related bacterial infections represent a major but under‐recognised health issue among people who inject drugs (PWID). Harm reduction interventions (HRIs) like needle and syringe programmes (NSP) and opioid agonist treatment (OAT) could mitigate their burden.
Anthony Cousien +7 more
wiley +1 more source
Clinical Need and Research Investment for Liver Cancer in Australia
Asia-Pacific Journal of Clinical Oncology, EarlyView.Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen +15 more
wiley +1 more source
Pooled prevalence, risk factors and barriers to care for hepatitis C virus (HCV) in adults with serious mental illness (SMI): an updated systematic review and meta-analysis - protocol. [PDF]
BMJ OpenMaryam S, Noor M, Kulsoom A.
europepmc +1 more source
Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
Allergy, EarlyView.We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source
MicroRNA-122 as a regulator and biomarker of liver disease. [PDF]
J Mol Med (Berl)Ahmadova S +7 more
europepmc +1 more source
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
Innovative management of hepatitis C: implementation and outcomes of the 'SMART' model in a general hospital. [PDF]
J Glob HealthLi M, Hu W, Dai Z, Li J, Ma J, Li Y.
europepmc +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub +2 more
wiley +1 more source
From Antigenic Drive to Clonal Autonomy: An Update on Molecular Mechanisms of HCV-Related B-Cell Lymphomagenesis. [PDF]
Cancers (Basel)Marri S +3 more
europepmc +1 more source
Epstein‐Barr virus as a driver of lupus: Rethinking triggers in autoimmunity
Rheumatology &Autoimmunity, EarlyView.
Jiekai Tan, Fanlei Hu, Chuanhui Xu
wiley +1 more source