Results 51 to 60 of about 13,487 (274)
Advanced NanoBiomed Research, EarlyView.CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source
HDR Image Construction from Trifocal Multiexposure Images
, 2021 With the progress of autonomous vehicles, the sensing of the environment in more detail with higher dynamic ranges has become more important to classify surrounding objects and obstacles.
Alper Koz +16 more
core +1 more source
An HDR imaging method with DTDI technology for push-broom cameras
Photonic Sensors, 2017 Conventionally, high dynamic-range (HDR) imaging is based on taking two or more pictures of the same scene with different exposure. However, due to a high-speed relative motion between the camera and the scene, it is hard for this technique to be applied
Wu Sun +10 more
doaj +1 more source
Extending and Matching a High Dynamic Range Image from a Single Image
Sensors, 2020 Extending the dynamic range can present much richer contrasts and physical information from the traditional low dynamic range (LDR) images. To tackle this, we propose a method to generate a high dynamic range image from a single LDR image. In addition, a
Van Luan Tran, Huei-Yung Lin
doaj +1 more source
HDR Imaging with One-Bit Quantization
2024 IEEE 13rd Sensor Array and Multichannel Signal Processing Workshop (SAM)Modulo sampling and dithered one-bit quantization frameworks have emerged as promising solutions to overcome the limitations of traditional analog-to-digital converters (ADCs) and sensors. Modulo sampling, with its high-resolution approach utilizing modulo ADCs, offers an unlimited dynamic range, while dithered one-bit quantization offers cost ...
Arian Eamaz +2 more
openaire +2 more sources
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
High Dynamic Range Image Reconstruction using Deep Learning
, 2023 reservedHDR image reconstruction is a technique that aims to generate high-quality images with a wider range of brightness and colors than traditional imaging methods In recent years, deep learning and residual networks have been utilized in various ...
GHARBI, MOURAD
core
Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor
Bulletin of the Korean Chemical Society, EarlyView.This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim +8 more
wiley +1 more source
Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Developmental Dynamics, EarlyView.Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source
International Journal of Cancer, EarlyView.Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim +22 more
wiley +1 more source