Results 61 to 70 of about 17,083,400 (305)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Auditory model based subsetting of Head-Related Transfer Function datasets [PDF]

, 2020
The rising availability of public head-related transfer function (HRTF) data, measured on hundreds of different individuals, offers a user the possibility to select the best matching non-individual HRTF from a wide catalogue.
Simone Spagnol, Spagnol, Simone, Spagnol, Simone; id_orcid   +2 more
core   +1 more source

Low-Order Spherical Harmonic HRTF Restoration Using a Neural Network Approach

Applied Sciences, 2020
Spherical harmonic (SH) interpolation is a commonly used method to spatially up-sample sparse head related transfer function (HRTF) datasets to denser HRTF datasets.
Benjamin Tsui, William A. P. Smith, Gavin Kearney   +2 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

A Two-Stage Deep Neural Network Approach to Personalized Head-Related Transfer Function Prediction

IEEE Access
Using non-personalized head-related transfer functions (HRTFs) in spatial audio reproduction often tends to cause perceptual inaccuracies such as localization blur, front-back confusion, and elevation localization errors.
Zifei Wang, Ruohua Zhou
doaj   +1 more source

Fast Measurement of Individual Head-Related Transfer Functions [PDF]

, 2019
Dissertation, RWTH Aachen University, 2019; Berlin : Logos Verlag Berlin GmbH, Aachener Beiträge zur Akustik 30, 1 Online-Ressource (III, 151 Seiten) : Illustrationen, Diagramme (2019).
openaire   +4 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Effect of Individualized Head-Related Transfer Functions on Distance Perception in Virtual Reproduction for a Nearby Sound Source

Archives of Acoustics, 2019
The head-related transfer function (HRTF) is dependent on the position of the sound source (both direction and distance) and is also affected by individual anatomical parameters.
Guangzheng YU, Liliang WANG
doaj   +1 more source

Virtual Reality Exploration With Different Head-Related Transfer Functions [PDF]

, 2018
(Abstract to follow)
Sikstrom E., Geronazzo M., Kleimola J., Avanzini F., De Gotzen A., Serafin S.   +5 more
openaire   +2 more sources