Results 71 to 80 of about 7,002,290 (342)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Head imaging and craniometry: A historical note on a base line error [PDF]

, 1995
This is the author's PDF version of an article published in Radiography today© 1995. Figure 1 and figure 2 are not available.This journal article discusses the work of Lysholm, Reid, and von Ihering in standarding patient positioning during radiological ...
Lewis, Stephen J.
core  

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Feasibility of a RCT of techniques for managing an impacted fetal head during emergency caesarean section: the MIDAS scoping study

Health Technology Assessment, 2023
Background: Second-stage caesarean sections, of which there are around 34,000 per year in the UK, have greater maternal and perinatal morbidity than those in the first stage.
Walker Kate F, Mitchell Eleanor J, Ayers Susan, Jones Nia W, Ogollah Reuben, Wakefield Natalie, Dorling Jon, Pallotti Phoebe, Pillai Arani, Tempest Nicola, Plachcinski Rachel, Bradshaw Lucy, Knight Marian, Thornton Jim G   +13 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Head Tracking via Robust Registration in Texture Map Images [PDF]

, 1997
A novel method for 3D head tracking in the presence of large head rotations and facial expression changes is described. Tracking is formulated in terms of color image registration in the texture map of a 3D surface model.
Isidoro, John, La Cascia, Marco, Sclaroff, Stan   +2 more
core  

Assessment of professional of the head of a socially-oriented establishment

Economic and Social Changes: Facts, Trends, Forecast, 2014
The estimate of efficient corporate governance, as well as professional activity of the subject of this process – a Manager – is one of the most important tasks of modern management.
Larisa Osipovna Kocheshkova
doaj   +1 more source

Head-to-head polymers: 34. Head-to-head poly(1-vinylnaphthalene)

Polymer, 1987
Abstract Head-to-head poly(1-vinylnaphthalene) was synthesized by a sequence of five reactions and the polymer was characterized by its infra-red and nuclear magnetic resonance spectra. Methyl 1-naphthylacetate was brominated to methyl 2-bromo-2(1-naphthyl)acetate, which was coupled with a copper-zinc couple to dimethyl 2,3-di(1-naphthyl)succinate, a
Liping Hu, Otto Vogl, Masato Nanasawa
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Ultraluminous X-ray Sources and Their Nebulae [PDF]

, 2008
One of the interesting features of Ultraluminous X-ray sources is that many of them are surrounded by luminous nebulae exhibiting diverse observational properties. In different cases the nebulae are photoionized or shock-powered.
Magnus Axelsson, Pavel Abolmasov
core   +1 more source