Results 91 to 100 of about 1,585,150 (380)

Metachronous immune-related adverse events involving type 1 diabetes and isolated adrenocorticotropic hormone deficiency associated with pembrolizumab monotherapy for metastatic head and neck cancer: a case report

Journal of Medical Case Reports, 2023
Background Immune checkpoint inhibitors might cause immune-related adverse events that are still largely unknown. Case presentation An 80-year-old Asian female was diagnosed with cervical lymph node metastasis from lip cancer (cT1N0M0) and underwent ...
Hiroaki Iijima, Akihiro Sakai, Koji Ebisumoto, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Toshihide Inagi, Kenji Okami   +7 more
doaj   +1 more source

Second primary cancer risk - the impact of applying different definitions of multiple primaries: results from a retrospective population-based cancer registry study [PDF]

, 2014
Background: There is evidence that cancer survivors are at increased risk of second primary cancers. Changes in the prevalence of risk factors and diagnostic techniques may have affected more recent risks.<p></p> Methods: We examined the
A Chopra, A Mehnert, Aishah Coyte, C Dong, C Fabbri, C Thellenberg, CH Johnson, D Brewster, D Brewster, D Brewster, D Forman, D Groheux, D Howel, David S Morrison, DM Parkin, DM Parkin, DR Youlden, E Crocetti, E Kellen, EM Ibrahim, F Levi, GB Yang, I Soerjomataram, IARC/ENCR/IACR Working Group, International Agency for Research on Cancer, J Ferlay, J Jegu, J Maddams, JA Atienza, JW Hotchkiss, K Hemminki, K Hemminki, K Moser, L Liu, L Liu, L Mellemkjaer, LJ Rutten, MB Adamo, MH Schmid-Wendtner, Philip McLoone, RE Curtis, S Scholes, X Gao, Y Chen   +43 more
core   +3 more sources

HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients.

Journal of the National Cancer Institute, 2016
BACKGROUND We conducted a large international study to estimate fractions of head and neck cancers (HNCs) attributable to human papillomavirus (HPV-AFs) using six HPV-related biomarkers of viral detection, transcription, and cellular transformation ...
X. Castellsagué, L. Alemany, M. Quer, G. Halec, B. Quirós, S. Tous, O. Clavero, L. Alós, T. Biegner, T. Szafarowski, M. Alejo, D. Holzinger, Enrique Cadena, E. Claros, G. Hall, J. Laco, M. Poljak, M. Benevolo, Elena Kasamatsu, H. Mehanna, C. Ndiaye, N. Guimerà, B. Lloveras, X. León, J. Ruiz-Cabezas, I. Alvarado-Cabrero, C. Kang, J. Oh, M. García-Rojo, Ermina Iljazović, O. Ajayi, Flora Duarte, A. Nessa, L. Tinoco, M. A. Durán-Padilla, E. Pirog, Halina Viarheichyk, Hesler Morales, V. Costes, A. Félix, M. Germar, M. Mena, A. Ruacan, Asha Jain, R. Mehrotra, M. Goodman, L. E. Lombardi, A. Ferrera, S. Malami, E. I. Albanesi, Pablo Dabed, C. Molina, Rubén López-Revilla, V. Mandys, Manuel E González, J. Velasco, I. Bravo, W. Quint, M. Pawlita, N. Muñoz, S. de Sanjosé, F. X. Xavier Bosch   +61 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Evaluation of pure-tone audiometric protocols in vestibular schwannoma screening

Journal of Otology, 2021
The objective was to evaluate the pure-tone audiogram-based screening protocols in VS diagnostics. We retrospectively analyzed presenting symptoms, pure tone audiometry and MRI finding from 246 VS patients and 442 controls were collected to test ...
Matej Vnencak, Elina Huttunen, Antti A. Aarnisalo, Jussi Jero, Katja Liukkonen, Saku T. Sinkkonen   +5 more
doaj  

Malignant peripheral nerve sheath tumor of the cervical vagus nerve in a neurofibromatosis type 1 patient - An unusual presentation [PDF]

, 2010
Malignant peripheral nerve sheath tumors (MPNST’S) of the head and neck comprise 2% to 6% of head and neck sarcomas. These tumors may arise as sporadic variants or in patients with neurofibromatosis (NF).
Bahl, A, Bansal, S, Bhagat, S, Gupta, A
core   +1 more source

The head and neck cancer immune landscape and its immunotherapeutic implications.

JCI Insight, 2016
Recent clinical trials have demonstrated a clear survival advantage in advanced head and neck squamous cell carcinoma (HNSCC) patients treated with immune checkpoint blockade.
Rajarsi Mandal, Y. Şenbabaoğlu, A. Desrichard, J. Havel, Martin G. Dalin, N. Riaz, Ken-Wing Lee, I. Ganly, A. Hakimi, T. Chan, L. Morris   +10 more
semanticscholar   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

IL-13 May Could Enhance the Proliferation and Affect the Differentiation of Nasal Epithelium Basal Cells Through the mTOR/p70S6K1 Pathway in Chronic Rhinosinusitis With Nasal Polyps

Mediators of Inflammation
Conclusion: IL-13 may affect the proliferation and differentiation of nasal epithelial progenitor/stem cells through the mTOR/p70S6K1 pathway, which may affect the development of nasal polyps.
Ping Li, Tao Li, Jinfeng Luo, Peng Yu, Tao Jiang, Xiangmin Zhou, Liang Yu, Aiping Chen, Yuzhu Wan, Li Shi   +9 more
doaj   +1 more source

Effects of BNO 1016 on ciliary transport velocity and cell culture surface liquid height of sinonasal epithelial cultures

Clinical Phytoscience, 2021
Background BNO 1016 is an ethanolic extract of a mixture of five herbs that has been sold in different formulations for decades in the European market and more recently, in the United States market as an over-the-counter treatment for rhinosinusitis ...
Alan D. Workman, Ivy W. Maina, Vasiliki Triantafillou, Neil N. Patel, Charles C. L. Tong, Edward C. Kuan, David W. Kennedy, James N. Palmer, Nithin D. Adappa, Noam A. Cohen   +9 more
doaj   +1 more source