Results 101 to 110 of about 3,900,516 (357)

Introduction and expression of PIK3CA E545K in a papillary thyroid cancer BRAF V600E cell line leads to a dedifferentiated aggressive phenotype

Journal of Otolaryngology - Head and Neck Surgery, 2022
Anaplastic thyroid cancer (ATC) is a rare, aggressive form of undifferentiated thyroid cancer, which exhibits rapid progression and is almost universally fatal.
Nicole Pinto, Kara M. Ruicci, Mohammed Imran Khan, Mushfiq Hassan Shaikh, Yu Fan Peter Zeng, John Yoo, Kevin Fung, S. Danielle MacNeil, Adrian Mendez, Joe S. Mymryk, John W. Barrett, Paul C. Boutros, Anthony C. Nichols   +12 more
doaj   +1 more source

Spontaneous Iliopsoas Hematoma following Microvascular Free Tissue Transfer. [PDF]

, 2017
Spontaneous hematoma within the iliopsoas muscle (SIH) is a rare complication most commonly seen in coagulopathic patients. Often, patients undergoing microvascular free tissue transfer are anticoagulated for anastomotic patency.
Alemi, A Sean, Faden, Daniel L, Heaton, Chase M, Markey, Jeffrey D, Naunheim, Margaret L, Seth, Rahul   +5 more
core   +2 more sources

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell

Neural Plasticity, 2022
Ototoxic hearing loss results from hair cell death via reactive oxygen species (ROS) overproduction and consequent apoptosis. We investigated the effects of vitamin C (VC) on neomycin-induced HEI-OC1 cell damage, as well as the mechanism of inhibition ...
Liang Gong, Biao Chen, Jingyuan Chen, Yongxin Li   +3 more
doaj   +1 more source

Head and Neck Pathology [PDF]

Surgical Pathology Clinics, 2017
Series Foreword Preface Acknowledgements 1. Squamous Cell Carcinoma - Variants: 1.1 Adenosquamous Carcinoa, 1.2 Basaloid squamous cell carcinoma, 1.3 hybrid verucous carcinoma, 1.4 Spindle cell squamous carcinoma, 1.5 Verrucous carcinoma - papillary keratosis 2.
openaire   +3 more sources

Are the demographics for squamous cell cancer in the head and neck changing in the United Kingdom? [PDF]

, 2007
Head and neck squamous cell carcinoma is well known to be more common in men than women. Smoking and alcohol are the key risk factors causing such malignancies and there are several publications which have suggested that the prevalence of these diseases ...
Hassan, MA, Howard, DJ, Lund, VJ, Sackert, AA   +3 more
core  

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Recommendations from the Canadian Association of Head and Neck Surgical Oncology for the Management of Head and Neck Cancers during the COVID-19 pandemic

Journal of Otolaryngology - Head and Neck Surgery, 2020
Introduction The SARS-CoV-2 virus (COVID19) pandemic has placed extreme pressures on the Canadian Healthcare system. Many health care regions in Canada have cancelled or limited surgical and non-surgical interventions on patients to preserve healthcare ...
Daniel A. O’Connell, Hadi Seikaly, Andre Isaac, Justin Pyne, Robert D. Hart, David Goldstein, John Yoo, Canadian Association of Head and Neck Surgical Oncology   +7 more
doaj   +1 more source

lncRNA FR215775 Regulates Th2 Differentiation in Murine Allergic Rhinitis

Journal of Immunology Research, 2022
To identify the effect of long noncoding RNA (lncRNA) FR215775 in regulating CD4+ T cells on murine models of allergic rhinitis (AR), the expression of lncRNA FR215775 in primary Th2 cells was detected through qRT-PCR.
Yue Ma, Le Shi, Keqing Zhao, Chunquan Zheng   +3 more
doaj   +1 more source