Results 121 to 130 of about 3,900,516 (357)
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
A New Model for Solving Narrow Escape Problem in Domain with Long Neck [PDF]
arXiv, 2014 The narrow escape problem arises in deriving the asymptotic expansion of the solution of an inhomogeneous mixed Dirichlet-Neumann boundary value problem. In this paper, we mainly deal with narrow escape problem in a smooth domain connected to a long neck-Dendritic spine shape domain, which has a certain significance in biology.
arxiv
Neck linker docking coordinates the kinetics of kinesin's heads [PDF]
, 2011 Conventional kinesin is a two-headed homodimeric motor protein, which is able to walk along microtubules processively by hydrolyzing ATP. Its neck linkers, which connect the two motor domains and can undergo a docking/undocking transition, are widely believed to play the key role in the coordination of the chemical cycles of the two motor domains and ...
arxiv +1 more source
Indian Journal of Plastic Surgery, 2013 ABSTRACTWhatever is excisable, is reconstructable! "You excise, we will reconstruct" are the confident words of reconstructive surgeons today. Reconstruction with multiple flaps has become routine. Radial artery (FRAF), Antero lateral thigh (ALT) and Fibula osteo cutaneous flap (FFOCF) are three most popular free flaps which can reconstruct any defect ...
openaire +4 more sources
Head and Neck Manifestations of Eosinophilic Granulomatosis with Polyangiitis: A Systematic Review. [PDF]
, 2016 OBJECTIVE: To conduct the first and only systematic review of the existing literature on head and neck manifestations of eosinophilic granulomatosis with polyangiitis to guide clinical decision making for the otolaryngologist.
Basnyat, Shristi +4 more
core +1 more source
Advanced Engineering Materials, EarlyView., 2023 This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng +3 more
wiley +1 more source
PPAR ResearchIt has been demonstrated that PPARG may interact with the PTEN-PI3K/AKT pathway, contributing to its involvement in the chemotherapy treatment of hypopharyngeal squamous cell carcinoma (HSCC). However, the underlying mechanism remains largely unknown. In
Boxuan Han +6 more
doaj +1 more source
Segmentation of Head and Neck Organs at Risk Using CNN with Batch Dice Loss [PDF]
arXiv, 2018 This paper deals with segmentation of organs at risk (OAR) in head and neck area in CT images which is a crucial step for reliable intensity modulated radiotherapy treatment. We introduce a convolution neural network with encoder-decoder architecture and a new loss function, the batch soft Dice loss function, used to train the network.
arxiv
Malignant peripheral nerve sheath tumor of the cervical vagus nerve in a neurofibromatosis type 1 patient - An unusual presentation [PDF]
, 2010 Malignant peripheral nerve sheath tumors (MPNST’S) of the head and neck comprise 2% to 6% of head and neck sarcomas. These tumors may arise as sporadic variants or in patients with neurofibromatosis (NF).
Bahl, A, Bansal, S, Bhagat, S, Gupta, A
core +1 more source
Head and neck paragangliomas: clinical and molecular genetic classification [PDF]
, 2012 Head and neck paragangliomas are tumors arising from specialized neural crest cells. Prominent locations are the carotid body along with the vagal, jugular, and tympanic glomus.
Boedeker, Carsten C +15 more
core +5 more sources