Results 181 to 190 of about 59,376 (244)
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
Advanced NanoBiomed Research, EarlyView.This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou +4 more
wiley +1 more source
Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy
Advanced NanoBiomed Research, EarlyView.This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei +3 more
wiley +1 more source
Nanoparticles Functionalized with Polymer Brushes for Gene Delivery
Advanced NanoBiomed Research, EarlyView.The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective This study aimed to ascertain the effect of secukinumab on erosion and enthesiophyte progression in psoriatic arthritis (PsA) by using high‐resolution peripheral quantitative computed tomography (HR‐pQCT). Methods This was a phase 4, double‐blind, randomized, placebo‐controlled trial.
Yingzhao Jin +11 more
wiley +1 more source
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Accepted Article.Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen +2 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Ryanodine receptor type 2 (RYR2) is a large calcium channel that has been identified as one of the most frequently mutated genes in lung adenocarcinoma (LUAD). Despite its potential significance, the role of RYR2 in LUAD remains poorly understood.
Tao Wang +3 more
wiley +1 more source
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, EarlyView.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
Cancer Stem Cell Characterization in Olfactory Neuroblastoma Tissue
International Forum of Allergy &Rhinology, EarlyView.
Shivani Ramolia +9 more
wiley +1 more source
X‐ray controlled release strategy in cancer therapy
BMEMat, EarlyView.A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan +5 more
wiley +1 more source