Results 201 to 210 of about 292,778 (314)

Mucoadhesive Polyvinyl Alcohol Film Containing Fridericia chica Extract for Mucositis Treatment: Pharmacological Evaluation and Active Compounds Release

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Oral mucositis is a frequent and painful complication of cancer therapy with limited effective options. This study evaluated a mucoadhesive polyvinyl alcohol (PVA) film containing 2.5% Fridericia chica extract as a novel strategy. The formulation was characterized for antioxidant activity, phenolic and flavonoid content, and reactive species ...
Ilza Maria de Oliveira Sousa   +12 more
wiley   +1 more source

In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target. [PDF]

open access: yesNat Commun
Fu C   +28 more
europepmc   +1 more source

Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds

open access: yesChemMedChem, EarlyView.
Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis   +3 more
wiley   +1 more source

Targeting the HIF1A-UCA1-PTBP3 axis: a potential therapeutic strategy for head and neck cancer. [PDF]

open access: yesBMC Cancer
Sim LC   +9 more
europepmc   +1 more source

Cyanostyryl‐Guanidiniocarbonyl‐Pyrrole Amphiphiles: From Aggregation‐Induced Emission to Photodimerization, Self‐Assembly, and Bioimaging

open access: yesChemPlusChem, EarlyView.
Amphiphiles with AIE properties, built on a novel luminophore containing an oxo‐anion binding motif, were synthesized and studied for self‐assembly in water. Carboxylate binding was verified by static quenching of a bound pyrene probe, and morphologies were analyzed by TEM, DLS, and ζ‐potential.
Kevin Rudolph   +10 more
wiley   +1 more source

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