Results 211 to 220 of about 698,058 (405)

P-230 Impact of COVID-19 pandemic on head-neck cancer referral and treatment pathway in North East London

, 2021
Arshad Zubair, Shiraz Jamshaid, Daniel W. Scholfield, Ahmad Hariri, Jahangir Ahmed, K Ghufoor, Safina Ali   +6 more
openalex   +2 more sources

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

Advanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang, Ruiying Qiang, Yuan Zhang, Jinxian Wan, Chen Tao, Ying Dong, Xujun Tang, Li Xu, Hairong Xiao, Yanqin Lin, Wei Tong, Ying Ma, Yongming Wang, Peng Li, Renjie Chai   +14 more
wiley   +1 more source

Measurement of tumor volume by PET to evaluate prognosis in patients with head and neck cancer treated by chemo-radiation therapy

, 2010
Young Mi Seol, Bo Ran Kwon, Gyung Hyuck Ko, Young Jin Choi, Ho Jin Shin, Joo Seop Chung, Goon Jae Cho, Jin Chun Lee, Byung‐Joo Lee, Soo Geun Wang, Hak Jin Kim, Won Taek Kim, Seung Jang Kim, Eun Young Yun   +13 more
openalex   +1 more source

HPV infections in head and neck cancers (HNSCC) – clinical course and efficiency of therapy [PDF]

, 2019
Mateusz Sikora, Magda Przesławska, Rafał Becht   +2 more
openalex   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

Advanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li, Tianqi Su, Bin Zhang, Wenkai Han, Sibin Zhang, Guiyin Sun, Yuwei Cong, Xin Chen, Jiping Qi, Yujie Wang, Shiguang Zhao, Hongxue Meng, Peng Liang, Xin Gao   +13 more
wiley   +1 more source

Special Issue "Pathogenesis and Treatments of Head and Neck Cancer". [PDF]

Int J Mol Sci
Tarle M.
europepmc   +1 more source

P2.17-24 Minimally Invasive Surgery for Lung Cancer Improves Short Term Outcomes in Patients with History of Head and Neck Carcinoma [PDF]

, 2019
David Boulate, Tchala Kassegne, Joséphine Chenesseau, Myriam Ammi, Sacha Mussot, Dominique Fabre, Délphine Mitilian, Adrian Crutu, Stéphane Temam, Olaf Mercier, Élie Fadel   +10 more
openalex   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source