Results 141 to 150 of about 152,721 (288)

Neoadjuvant Cemiplimab for Resectable Locoregionally Advanced Cutaneous Squamous Cell Carcinoma: A Case Series

Head &Neck, EarlyView.
ABSTRACT Introduction A Phase II trial demonstrated that neoadjuvant cemiplimab was associated with pathologic complete response (pCR) in 51% of patients with locoregionally advanced cutaneous squamous cell carcinoma (cuSCC). We evaluated real‐world radiographic and pathologic responses to neoadjuvant cemiplimab and assessed radiologic–pathologic ...
Whitney Jin, Ryan K. Rigsby, Kim Ely, Austin Hoke, Robert Sinard, Kyle Mannion, Jill Gilbert, Lindsay Mundy, Alexander Langerman, Sarah Rohde, Barbara Murphy, Eben Rosenthal, Mitra Mehrad, Michael C. Topf, Jennifer H. Choe   +14 more
wiley   +1 more source

Aggressive Mandibular Squamous Cell Carcinoma Mimicking Periodontal Disease in a Non‐Transplanted Patient With Fanconi Anemia

Head &Neck, EarlyView.
ABSTRACT Background Fanconi anemia (FA) is associated with markedly increased risk for early‐onset oral squamous cell carcinoma (OSCC). Methods We report an aggressive mandibular squamous cell carcinoma in a 26‐year‐old non‐transplanted woman with FA initially interpreted as localized periodontal disease adjacent to a tongue leukoplakia.
Cassius Carvalho Torres‐Pereira, Laura Grein Cavalcanti, Marta Aparecida Alberton Nuernberg, Juliana Lucena Schussel, José Miguel Amenábar Céspedes   +4 more
wiley   +1 more source

Assesment of angiogenesis in basal cell carcinoma using CD31 &CD34 markers and relation with tumor invasiveness in histology [PDF]

Background & Objective : Tumor angiogenesis is essential for tumor growth and appears to play an importating role both in invasive growth and metastasis.
صفايی, زهرا, حديثی, مهدی, فتحي, سولماز, امانی, فیروز   +3 more
core  

Bone‐Anchored Implant Survival in Oncologic Facial Prosthetic Rehabilitation

Head &Neck, EarlyView.
ABSTRACT Background Published survival rates for bone‐anchored craniofacial implants exceed 85%, but derive largely from mixed populations. Whether these apply to head and neck oncologic surgery remains uncertain. Methods Retrospective survival analysis of implants placed for prosthetic rehabilitation following extirpative surgery at a UK center (2005 ...
Oliver Blanshard, Sarah Jones, Peter M. Clarke, Jonathan M. Bernstein   +3 more
wiley   +1 more source

Complete Pathologic Response to Neoadjuvant Pembrolizumab Captured on Intraoperative PET/CT: A Case Report and Exploratory Analysis

Head &Neck, EarlyView.
ABSTRACT Background Neoadjuvant immunotherapy is an emerging treatment for patients with head and neck cancer. Given the heterogeneity of response, novel methods of intraoperative tumor and margin assessment warrant investigation. Methods A 55‐year‐old male presented with a cT3N2c supraglottic squamous cell carcinoma with a combined positive score of 5.
Joaquin Austerlitz, Andreja Radevic, Ashtyn McAdoo, Kyrionna Golliday, Cassie Pan, Annie Moroco, Spencer Roark, Michael C. Topf   +7 more
wiley   +1 more source

Pattern of Failure in Nasopharyngeal Carcinoma After Radiotherapy in a Low‐Incidence Population: A DAHANCA Study

Head &Neck, EarlyView.
ABSTRACT Background Nasopharyngeal carcinoma (NPC) is uncommon in many populations. Most existing clinical evidence comes from endemic areas, where Epstein–Barr virus (EBV)‐associated subtypes predominate. We analyzed patterns of failure in a population‐based cohort from Denmark, a low‐incidence setting.
Anne Marie Lindegaard, Katrin Haakansson, Maria Andersen, Mogens Bernsdorf, Jesper G. Eriksen, Mohammad Farhadi, Lisa L. Hjalgrim, Kenneth Jensen, Giedrius Lelkaitis, Christian Maare, Jens Overgaard, Christina Caroline Plaschke, Erik Schiess, Ruta Zukuskaite, Jeppe Friborg   +14 more
wiley   +1 more source

Characterization of Perineural Invasion Parameters for Risk Stratification in Oral Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) is an established adverse prognostic factor in oral squamous cell carcinoma (OSCC), but the implications of its extent as well as its relationship with surgical margin status and the extent of microscopic tumor spread remain unclear.
Michael A. Müller, Muriel D. Brada, Niels J. Rupp, Cosima E. Riemenschnitter, Simon Müller, Alexander M. Huber, Panagiotis Balermpas, Grégoire B. Morand   +7 more
wiley   +1 more source

Multiregion profiling of genomic and transcriptional heterogeneity in head and neck squamous-cell carcinoma. [PDF]

ESMO Open
Heurtier V, Marret G, Lamy C, Hamza A, Diallo MH, Ahmanache L, Vacher S, Schnitzler A, Courtois L, Jeannot E, Klijanienko J, El Beaino Z, Gal J, Ledru M, Martinat C, Martin J, Choussy O, Dubray-Vautrin A, Lesnik M, Ghanem W, Taouachi R, Badois N, Nhy C, Borcoman E, Flavius J, Kadi A, Berger F, Servant N, Kamal M, Bièche I, Le Tourneau C.   +30 more
europepmc   +1 more source

Predicting Oral Cancer From Precursor Lesions: The Case for a Standardized Framework of Analysis to Improve Prediction Modeling

Head &Neck, EarlyView.
ABSTRACT Oral Cancer often occurs from the transformation of precursor lesions, and this offers an opportunity for early detection. Current methods to assess risk of precursor lesion progression to oral cancer incompletely predict risk. A multimodal framework that leverages machine learning is needed to improve prediction.
Michael E. Troka, James C. Gates
wiley   +1 more source

Prognostic Value of FST and Relevance to Immune Infiltration in Head and Neck Squamous Cell Carcinoma. [PDF]

World J Otorhinolaryngol Head Neck Surg
Song P, Wu TW, Wang JY, Ye YC, Liang FY, Huang XM, Han P.   +6 more
europepmc   +1 more source