Results 131 to 140 of about 523,743 (349)

Whether Detection of Gene Mutations Could Identify Low- or High-Risk Papillary Thyroid Microcarcinoma? Data from 393 Cases Using the Next-Generation Sequencing

open access: yesInternational Journal of Endocrinology
Objective. The objective of this study is to explore the utilization of next-generation sequencing (NGS) technology in evaluating the likelihood of identifying individuals with papillary thyroid microcarcinoma (PTMC ≤10 mm) who are at high or low risk ...
Lei Jin   +8 more
doaj   +1 more source

Treatment with preoperative irradiation and surgery of squamous cell carcinoma of the head and neck [PDF]

open access: bronze, 1989
Zhonghe Wang   +4 more
openalex   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

open access: yesAdvanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Otorhinolaryngology - Head and Neck Surgery [PDF]

open access: yes, 2007
中川 肇   +12 more
core   +6 more sources

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Jefferson Alumni Bulletin – Volume XLVIII, Number 1, March 1999 [PDF]

open access: yes, 1999
Jefferson Alumni Bulletin – Volume XLVIII, Number 1, March 1999 Otolaryngology-Head and Neck Surgery, Page 4 Gene Therapy in a Liquid: an Easier Treatment, Page 10 Gene Repair Technique is Developed, Page 10 Moving Closer to Gene Therapy for Lung Cancer,

core   +1 more source

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