Results 171 to 180 of about 523,743 (349)

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

Altered Nasal Microbiota-Metabolome Interactions in Allergic Rhinitis: Implications for Inflammatory Dysregulation

Journal of Inflammation Research
Qianzi Ma,1,2 Nan Wang,3 Xingyue Zheng,1 Junjie Liu,1 Yanlu Che,4 Jingting Wang2 1Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Harbin Medical University, Harbin, People’s Republic of China; 2Department of ...
Ma Q, Wang N, Zheng X, Liu J, Che Y, Wang J   +5 more
doaj  

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Augmented Reality Navigation in Craniomaxillofacial/Head and Neck Surgery. [PDF]

OTO Open
Strong EB, Patel A, Marston AP, Sadegh C, Potts J, Johnston D, Ahn D, Bryant S, Li M, Raslan O, Lucero SA, Fischer MJ, Zwienenberg M, Sharma N, Thieringer F, El Amm C, Shahlaie K, Metzger M, Strong EB.   +18 more
europepmc   +1 more source

Surgery in elderly patients with head and neck cancer.

, 1984
Akio Yoshida, Ken Okamoto, Ryuji Nagano
openalex   +2 more sources

Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy

Advanced Science, EarlyView.
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley   +1 more source

Quantifying capacity of otolaryngology-head and neck surgery in Zimbabwe. [PDF]

Laryngoscope Investig Otolaryngol
Green KJ, Eyassu DG, Jain A, Arya P, Candelo E, Douse DM, Matinhira NN, Chidziva C, Wiedermann JP.   +8 more
europepmc   +1 more source

Reconstructive Surgery for Head and Neck Cancer

, 1985
C Takeda, Yoshiaki Tai, K Washizu, Akihito Nagano, Sumio Matsuura   +4 more
openalex   +2 more sources

Avoiding Transfusion in Head and Neck Surgery: Feasibility Study of Erythropoietin [PDF]

, 2000
Erich M. Sturgis, Gerard J. Gianoli, Robert H. Miller, James W. Fisher   +3 more
openalex   +1 more source

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

Advanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao, Jiawei Zhou, Chen‐Chen Wang, Zong‐Hao Wang, Nian‐Dong Mao, Meng‐Lan He, Peng‐Peng Zhang, Ping Huang, Guo‐Wei Ye, Yu‐Qing Zhang, Feng‐Hui Tang, Hang Zhang, Tian Xie, Xiang‐Yang Ye   +13 more
wiley   +1 more source