Results 11 to 20 of about 285,920 (202)

Identification of RNA Modification-Associated Alternative Splicing Signature as an Independent Factor in Head and Neck Squamous Cell Carcinoma

Journal of Immunology Research, 2022
Objective. Head and neck squamous cell carcinoma (HNSCC) is a highly heterotopic malignant tumor. Alternative splicing (AS) and RNA modification have been reported to be involved in tumorigenesis. Therefore, we constructed RNA modification-associated AS (
Jie Liu, Wenmin Deng, Zhiwen Xiao, Xiaofeng Huang, Minmin Lin, Zhen Long   +5 more
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A Cell Component-Related Prognostic Signature for Head and Neck Squamous Cell Carcinoma Based on the Tumor Microenvironment

International Journal of Genomics, 2022
Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease with a high mortality rate. The tumor microenvironment (TME) is composed of numerous noncancerous cells that contribute to tumorigenesis and prediction of therapeutic effects.
Siyu Li, Yajun Gu, Junguo Wang, Dengbin Ma, Xiaoyun Qian, Xia Gao   +5 more
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Role of PPARG in Chemosensitivity-Regulating Network for Hypopharyngeal Squamous Cell Carcinoma

PPAR Research, 2023
PPARG has been reported to promote chemosensitivity in hypopharyngeal squamous cell carcinoma (HSCC). However, few studies tested its significance in the texture of a complex molecular network regulating chemosensitivity in HSCC.
Fanyong Kong, Boxuan Han, Jiaming Chen, Xixi Shen, Lizhen Hou, Jugao Fang, Meng Lian   +6 more
doaj   +1 more source

The Role of Noncoding RNA in Airway Allergic Diseases through Regulation of T Cell Subsets

Mediators of Inflammation, 2022
Allergic rhinitis and asthma are common airway allergic diseases, the incidence of which has increased annually in recent years. The human body is frequently exposed to allergens and environmental irritants that trigger immune and inflammatory responses,
Shenghao Cheng, Qingping Tang, Shaobing Xie, Sihui Wen, Hua Zhang, Zhihai Xie, Weihong Jiang   +6 more
doaj   +1 more source

Evaluation of Intralymphatic Immunotherapy in Allergic Rhinitis Patients: A Systematic Review and Meta-analysis

Mediators of Inflammation, 2023
Background. Intralymphatic immunotherapy (ILIT) is short-course administration of allergen-specific immunotherapy (AIT). This study is aimed at assessing the clinical efficacy and safety of ILIT in patients with allergic rhinitis (AR). Methods.
Sijie Jiang, Shaobing Xie, Qingping Tang, Hua Zhang, Zhihai Xie, Junyi Zhang, Weihong Jiang   +6 more
doaj   +1 more source

The Role of the P1 Latency in Auditory and Speech Performance Evaluation in Cochlear Implanted Children

Neural Plasticity, 2022
Auditory deprivation affects normal age-related changes in the central auditory maturation. Cochlear implants (CIs) have already become the best treatment strategy for severe to profound hearing impairment.
Shan Xiong, Liwei Jiang, Yu Wang, Tao Pan, Furong Ma   +4 more
doaj   +1 more source

Abducens Nerve Neuropraxia due to Acute Bacterial Rhinosinusitis: Case Report and Literature Review

Case Reports in Otolaryngology, 2023
Background. Acute bacterial rhinosinusitis (ABRS) is a common infection of the paranasal sinuses that can lead to complications such as orbital and intracranial extension. The abducens nerve course is adjacent to the sphenoid sinus.
Abdulrahman Alghulikah, Sarah Alseneidi, Hedayah Alsaady, Ahmed Alhussien, Surayie Al-Dousary, Saud Alromaih, Abdulrahman AlHumaizi   +6 more
doaj   +1 more source

Peripheral Multiple Cytokine Profiles Identified CD39 as a Novel Biomarker for Diagnosis and Reflecting Disease Severity in Allergic Rhinitis Patients

Mediators of Inflammation, 2023
Background. Allergic rhinitis (AR) is a common clinical problem, and immune cells and cytokines were proven to be pivotal in its pathogenesis. Our aim is to measure the peripheral concentrations of multiple cytokines in AR patients and identify novel ...
Yuanwei Jiang, Weiqun Hu, Zhifu Cai, Chaofan Lin, Shengnan Ye   +4 more
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Canadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis

Journal of Otolaryngology - Head and Neck Surgery, 2021
Background Recent evidence suggests that biologic therapy with targeted activity within the Type 2 inflammatory pathway can improve the clinical signs and symptoms of chronic rhinosinusitis with nasal polyposis (CRSwNP).
Andrew Thamboo, S. Kilty, I. Witterick, Y. Chan, C. J. Chin, A. Janjua, A. Javer, J. Lee, E. Monterio, B. Rotenberg, J. Scott, K. Smith, D. D. Sommer, L. Sowerby, M. Tewfik, E. Wright, M. Desrosiers   +16 more
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Metachronous immune-related adverse events involving type 1 diabetes and isolated adrenocorticotropic hormone deficiency associated with pembrolizumab monotherapy for metastatic head and neck cancer: a case report

Journal of Medical Case Reports, 2023
Background Immune checkpoint inhibitors might cause immune-related adverse events that are still largely unknown. Case presentation An 80-year-old Asian female was diagnosed with cervical lymph node metastasis from lip cancer (cT1N0M0) and underwent ...
Hiroaki Iijima, Akihiro Sakai, Koji Ebisumoto, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Toshihide Inagi, Kenji Okami   +7 more
doaj   +1 more source