Results 61 to 70 of about 523,743 (349)

A Complex Network of Obesity-Risk Genes Revealed by Systematic Bioinformatics and Single-Cell Transcriptomic Analyses

Journal of Obesity
The development of obesity is closely linked to genetic factors. Despite the identification of numerous genes associated with an increased risk of obesity in humans, a comprehensive understanding of their biological roles has not been achieved.
Yuenan Liu, Haolin Yuan, Junhui Hu, Xu Xu, Shankai Yin, Yiming Hu, Feng Liu   +6 more
doaj   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber‐Unkel, Annette Affolter, Paul Gatenholm, Nicole Rotter, Karen Bieback   +7 more
wiley   +1 more source

HPV & head and neck cancer: a descriptive update [PDF]

, 2015
The incidence of head and neck squamous cell carcinoma (HNSCC) has been gradually increasing over the last three decades. Recent data have now attributed a viral aetiology to a subset of head and neck cancers.
Bernal Sprekelsen, Manuel, Ebmeyer, Jörg, Goon, Peter K., Görner, Martin, Jerjes, Waseem, Stanley, Margaret, Steinsträsser, Lars, Sudhoff, Holger H., Upile, Tahwinder   +8 more
core   +2 more sources

PPARG and the PTEN-PI3K/AKT Signaling Axis May Cofunction in Promoting Chemosensitivity in Hypopharyngeal Squamous Cell Carcinoma

PPAR Research
It has been demonstrated that PPARG may interact with the PTEN-PI3K/AKT pathway, contributing to its involvement in the chemotherapy treatment of hypopharyngeal squamous cell carcinoma (HSCC). However, the underlying mechanism remains largely unknown. In
Boxuan Han, Jiaming Chen, Shaoshi Chen, Xixi Shen, Lizhen Hou, Jugao Fang, Meng Lian   +6 more
doaj   +1 more source

3D‐Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
3D‐printed organoid scaffolds with microscale channels are developed to enhance spinal cord injury recovery by guiding region‐specific spinal neural progenitor cells. These scaffolds promote axonal growth, cell maturation, and neuronal network formation.
Guebum Han, Nicolas S. Lavoie, Nandadevi Patil, Olivia G. Korenfeld, Hyunjun Kim, Manuel Esguerra, Daeha Joung, Michael C. McAlpine, Ann M. Parr   +8 more
wiley   +1 more source

Trismus following different treatment modalities for head and neck cancer: a systematic review of subjective measures [PDF]

, 2017
The aim of this review was to compare systematically the subjective measure of trismus between different interventions to treat head and neck cancer, particularly those of the oropharynx. Using The Preferred Reporting Items for Systematic Review and Meta-
Elhassan, Hassan, Loh, Sook Yin, McLeod, Robert William J.   +2 more
core   +2 more sources

Head and Neck Surgery [PDF]

Otolaryngology–Head and Neck Surgery, 2017
  +9 more sources

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

A thermoplastic vest to prevent self mutilation in experimental flap surgery in rats [PDF]

, 2012
Poster presented at: 8th International Conference on Head and Neck Cancer in Toronto, Canada. Introduction: Rats are frequently utilized for both research and training related to reconstructive head and neck surgery.
Drejet, MD, Sarah M, Gordin, MD, Eli A., Heffelfinger, MD, Ryan N.   +2 more
core   +1 more source

The orbit space of groupoids whose $C^*$-algebras are GCR

, 2017
Let $G$ be second countable locally compact Hausdorff groupoid with a continuous Haar system. We remove the assumption of amenability in a theorem by Clark about GCR groupoid $C^*$-algebras.
Erasmus MC other, Erasmus University Rotterdam, Franken, Marie-Christine, Goedegebure, André, le Clercq, Carlijn M. P., Otorhinolaryngology and Head and Neck Surgery, Rispens, Judith E., Ruytjens, Liesbet, University of Amsterdam, van der Schroeff, Marc P., van Ingen, Gijs   +10 more
core   +2 more sources