Results 61 to 70 of about 302,747 (255)

Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface

Advanced Science, EarlyView.
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu, Chen‐Xi Yue, Wen‐Zhong Dong, Cui‐Yun Hao, Yi‐Fan Qiao, Di Liu, Xin Zhang, Qi Zhan, Jia‐Bao Yao, Dong‐Ping Wang, Peng Cao, Ying‐Zhe Fan, Ye Yu   +12 more
wiley   +1 more source

Associations Among Obstructive Sleep Apnea, Thyroid Function and Morphology Changes

Nature and Science of Sleep
Yushan Xie,1,2,* Hongli Zhang,3,* Zine Cao,1,* Yanuo Zhou,1,2 Chendi Lu,1,2 Libo Yin,4 Simin Zhu,1,2 Yonglong Su,1,2 Xiaoxin Niu,1,2 Lina Ma,1,2 Yuqi Yuan,1,2 Yitong Zhang,1,2 Zitong Wang,1,2 Haiqin Liu,1,2 Xiaoyong Ren,1,2 Yewen ...
Xie Y, Zhang H, Cao Z, Zhou Y, Lu C, Yin L, Zhu S, Su Y, Niu X, Ma L, Yuan Y, Zhang Y, Wang Z, Liu H, Ren X, Shi Y   +15 more
doaj  

JAMA Otolaryngology–Head & Neck Surgery [PDF]

, 2017
Phil Fontanarosa, Annette Flanagin, Brenda Deputy, Ḿanaging Editor, Lauren Fischer, Karen Boyd, John Mcfadden, Gabriel Dietz, Rochelle Lodder, Sam Wilder, Connie Manno, Sara Billings, Timothy Gray, Catherine Alden, Stephanie Beckmeyer, Jane Calayag, Jan Clavey, Mary Coerver-Connolly, Paula Glitman, Laura King, Brandy Patton, Donna Thordsen, Editorial Assistant, Wanda Hill, Larry Bryant, Monica Mungle, Elaine Managers, Fanny Staff, Lenette Brown, Erin Gardner-Gullens, Peter Kato, Rachell Kim, Michaela Lozano, Caroline Mark, Elizabeth Sietmann, Michael Berkwits, Michelle Kurzynski, Eric Butkus, Carrie Butt, Mary Ferkaluk, Daniel Morrow, Reuben Rios, Ronna Henry, Karen Bucher, Andy Rekito, Emily Ling, David Song, Deputy Livingston, Thomas Cole, Marla Hall, Deanna Willis, Yolanda Davis, Joseph Thornton, Deanna Bellandi, Jim Periodical, Thomas Easley, Brian Shields, Karen Adams-Taylor, Monica Smith, Jeff Ery, J Bonistalli, Kathy Russell, Mirna Monal, Tim Melroy, Marketing Thornbury, Tricia Classifi, Thalia Moss, Susan Henning, Tiff Stevenson, Susan Lovenberg, Saskia Bolore, Gretchen Linder, Brian Mccartney, Christine Hearne, Rebecca Lisek, David Baum, Natasha Nekola, Ron Thomas, Paul Gee, Matt Herron, Elizabeth Solaro, Geoff Rey, Rick Bell, Fergus Clare, Lindsay Dawson, Will English, Ellen Gibson, Mustafa Ishaq, Craig Mccaff Rey, Michael Mcgraw, Daniel Pickhardt, Romando Rossini, Stacy Business, Analyst Sirisha, Alluri Staff, Millette Jackson-Bates, Karl Elvin, Nancy Essex, Jaye Mize, Sean O'donnell   +99 more
openalex   +1 more source

Impact of the COVID-19 Pandemic on Brazilian Head and Neck Surgery Centers

, 2023
Gustavo Fernandes de Alvarenga, Ana Kober Nogueira Leite, Carlos Neutzling Lehn, Rogério Aparecido Dedivitis, Marianne Yumi Nakai, Beatriz Godói Cavalheiro, Gilberto Teixeira, Rafael De Cicco, Luiz Paulo Kowalski, Leandro Luongo Matos   +9 more
openalex   +1 more source

Unplanned Hospital Readmission and Visit to the Emergency Room in the First Thirty Days after Head and Neck Surgery: A Prospective, Single-center Study [PDF]

, 2021
Carlos M. Chiesa‐Estomba, Jon Alexander Sistiaga-Suárez, José A. Gónzalez-García, Ekhiñe Larruscain Sarasola, Ariadna Valldeperes, Xabier Altuna   +5 more
openalex   +1 more source

Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials

Advanced Science, EarlyView.
LIRA, a machine learning‐based model, is developed using transcriptomic data from 891 NSCLC patients in the OAK and POPLAR cohorts. Its predictive performance is validated in multiple external cohorts. Patients stratified by LIRA‐score exhibit distinct clinical characteristics and tumor microenvironment profiles.
Zhaojun Wang, Yiran Fang, Xiatong Huang, Guichuang Ma, Qianqian Mao, Xiansheng Lu, Guangda Rong, Yunfang Yu, Yuanyuan Wang, Zhenhua Huang, Huiying Sun, Jiani Wu, Wenchao Gu, Na Huang, Jianhua Wu, Rui Zhou, Xiaoxiang Rong, Siting Zheng, Shaowei Li, Gaofeng Wang, Ling Wang, Wenjun Qiu, Luyang Jiang, Peng Luo, Yonggang Liu, Jianping Bin, Yulin Liao, Min Shi, Zuqiang Wu, Jiguang Wang, Wangjun Liao, Gang Chen, Dongqiang Zeng   +32 more
wiley   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

A Submucosal Moderately Poor Differentiated Laryngeal Squamous Cell Carcinoma Presenting as a Thyroid Mass: A Report of a New Case

Case Reports in Otolaryngology
Conclusion: SLC should be taken into consideration in the case of suspicious TC with laryngeal cartilage infiltration and subglottic area infiltration.
Zhihan Liu, Meng Lei, Ruimin Zhao, Xiaobao Yao, Yanxia Bai, Shaoqiang Zhang   +5 more
doaj   +1 more source

JAMA Otolaryngology–Head & Neck Surgery [PDF]

, 2019

openalex   +1 more source

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source