Results 81 to 90 of about 302,747 (255)

Palliative endoscopic treatment of malignant central airway obstruction

open access: yesBMC Pulmonary Medicine
Purpose To examine the outcome of palliative endoscopic treatment of malignant central airway obstruction (CAO) and identify predictors for Days Alive and Out of Hospital (DAOH), overall survival and treatment related complications.
Mads Bøgh   +6 more
doaj   +1 more source

Molecular Characterization of Lipoaspirates Used in Regenerative Head and Neck Surgery [PDF]

open access: bronze, 2019
Kariem Sharaf   +8 more
openalex   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Integrin αvβ6‐Targeted PET/CT Imaging of Non‐Small Cell Lung Cancer with [68Ga]Ga‐Trivehexin: Improved Preoperative Lymph Node Staging and Association with Immunohistochemistry

open access: yesAdvanced Science, EarlyView.
Integrin αvβ6‐targeted [68Ga]Ga‐Trivehexin positron emission tomography/computed tomography (PET/CT) can accurately identify regional lymph nodes and cerebral metastases in non‐small cell lung cancer (NSCLC) compared with 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG).
Huiqin Wu   +9 more
wiley   +1 more source

A phase 2 trial of a topical antiseptic bundle in head and neck cancer surgery: Effects on surgical site infection and the oral microbiome [PDF]

open access: gold, 2022
Joseph Zenga   +19 more
openalex   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin Sam George, Anthony J. Ricci
wiley   +1 more source

Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways

open access: yesAdvanced Science, EarlyView.
Decoding sound from neural activity in mice reveals a striking shift in how the brain encodes sound: from precise but redundant timing codes in early auditory areas to efficient, synergistic rate‐based codes in the cortex. This transformation highlights a robust neural strategy for turning complex acoustic input into coherent perception across the ...
Alexa Buck   +7 more
wiley   +1 more source

Sleep-Disordered Breathing as a Mediator Between Premature Birth and Behavior Problems in School-Aged Children: A Cross-Sectional Study of 6–10 Year Olds in Shanghai, China

open access: yesNature and Science of Sleep
Yuli Hu,1,2,* Siqiong Jiang,1,* Shiyin Yang,3 Chunsheng Wang,4 Jianyin Zou,5 Jian Guan,5 Yupu Liu,5 Qunfeng Lu1,2 1Nursing Department of Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine ...
Hu Y   +7 more
doaj  

Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning   +11 more
wiley   +1 more source

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