Optimising the assessment of cerebral autoregulation from black box models
, 2014 Cerebral autoregulation (CA) mechanisms maintain blood flow approximately stable despite changes in arterial blood pressure. Mathematical models that characterise this system have been used extensively in the quantitative assessment of function ...
Angarita-Jaimes, N. +4 more
core +1 more source
Impulsivity Relates to Relative Preservation of Mesolimbic Connectivity in Patients with Parkinson Disease. [PDF]
, 2020 IntroductionThe relationship between Parkinson Disease (PD) pathology, dopamine replacement therapy (DRT), and impulse control disorder (ICD) development is still incompletely understood.
Bari, Ausaf +6 more
core
Video head impulse testing to differentiate vestibular neuritis from posterior circulation stroke in the emergency department: a prospective observational study [PDF]
, 2022 James Thomas +10 more
openalex +1 more source
Hard‐Magnetic Soft Millirobots in Underactuated Systems
Advanced Robotics Research, EarlyView.This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang +4 more
wiley +1 more source
X-Rays from long laboratory sparks in air [PDF]
, 2016 This collective book provides a review of research concentrated on runaway electron beams and X-rays in an inhomogeneous electric field with different gases at increased pressure.
Kochkin, Pavlo +2 more
core +2 more sources
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury
Advanced Science, EarlyView.IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang +18 more
wiley +1 more source
Shifts in shuttle SRM performance because of ammonium perchlorate crystal shape on missions 51-I/J and 61-A/B [PDF]
The design of the Space Shuttle vehicle configuration requires that the SRMs produce thrust within tightly-controlled limits. These limits provide assurance that Shuttle ascent performance goals will be achieved within the vehicle flight load constraints.
Blackwell, D. L.
core +1 more source
Advanced Science, EarlyView.A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun +23 more
wiley +1 more source
Six-canal video head impulse test in patients with labyrinthine and retrolabyrinthine pathology: detecting vestibulo-ocular reflex deficits [PDF]
, 2022 Georgios Kontorinis +3 more
openalex +1 more source