Results 151 to 160 of about 219,201 (335)

Implementation and extension of the impulse transfer function method for future application to the space shuttle project. Volume 1: Analysis and correlation studies [PDF]

open access: yes
Computer programming, data processing, and a correlation study that employed data collected in the first phase test were used to demonstrate that standard test procedures and equipment could be used to collect a significant number of transfer functions ...
Mantus, M., Pardo, H.
core   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong   +8 more
wiley   +1 more source

The Value of the Video Head Impulse Test in Aerospace Medicine

open access: yesHanggong uju uihakoeji
The video head impulse test (vHIT) is an advanced diagnostic tool that provides objective, quantitative assessment of vestibulo-ocular reflex function across all six semicircular canals (SCCs).
Yang Seon Choi   +2 more
doaj   +1 more source

Apollo 7 CSM 101 service propulsion system, flight evaluation [PDF]

open access: yes
Flight performance of command module service propulsion system during Apollo 7 ...

core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

open access: yesAdvanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman   +15 more
wiley   +1 more source

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

open access: yesAdvanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková   +5 more
wiley   +1 more source

Orbit transfer vehicle engine study. Volume 1: Executive summary [PDF]

open access: yes
The orbit transfer vehicle (OTV) engine study provided parametric performance, engine programmatic, and cost data on the complete propulative spectrum that is available for a variety of high energy, space maneuvering missions.

core   +1 more source

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