Results 41 to 50 of about 26,359 (249)

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The video Head Impulse Test (vHIT) detects vertical semicircular canal dysfunction. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The video head impulse test (vHIT) is a useful clinical tool to detect semicircular canal dysfunction. However vHIT has hitherto been limited to measurement of horizontal canals, while scleral search coils have been the only accepted method ...
Hamish Gavin Macdougall   +4 more
doaj   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein   +7 more
wiley   +1 more source

Head Impulse Test

open access: yesAn International Journal of Otorhinolaryngology Clinics, 2012
ABSTRACTIn 1988, Michael Halmagyi and Ian Curthuoys described a simple yet reliable indicator of unilateral peripheral vestibular deficits at the bedside. This ‘head impulse test’ (HIT) as is has been known since, has stood the test of being a reliable indicator of vestibular deficit, especially for the horizontal semicircular canal.The test has been ...
openaire   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal   +2 more
wiley   +1 more source

Functional testing of the vestibular ocular reflex (VOR)

open access: yesFrontiers in Neurology, 2012
The experimental assessment of the vestibulo-ocular-reflex (VOR) gain provides an objective and quantitative measure of VOR performance which is nonetheless difficult to correlate with its efficiency in everyday living conditions.
Stefano eRamat   +10 more
doaj   +1 more source

Compensatory saccade in the vestibular impaired monkey

open access: yesFrontiers in Neurology, 2023
IntroductionLoss of the vestibulo-ocular reflex (VOR) affects visual acuity during head movements. Patients with unilateral and bilateral vestibular deficits often use saccadic eye movements to compensate for an inadequate VOR.
Yoshiko Kojima   +4 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

Prototipo de video frenzel-video head impulse test de bajo coste

open access: yesCiencia y Salud, 2019
Antecedentes: desde la introducción de las gafas de Frenzel se han desarrollados múltiples sistemas que permiten no permiten no solo observar el nistagmo, sino documentarlo y valorar su evolución y respuesta al tratamiento; pero el costo pero el costo de
Frank Alberto Betances Reinoso   +3 more
doaj   +1 more source

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