Results 51 to 60 of about 1,104,821 (294)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Characterization of head movement patterns in patients with bilateral and unilateral vestibulopathy during functional mobility tasks

Frontiers in Neuroscience
IntroductionBilateral and unilateral vestibulopathies mainly cause chronic imbalance/unsteadiness and oscillopsia, significantly impacting quality of life. Traditional clinical tests fail to assess functional impact on daily activities.
Gautier Grouvel, Gautier Grouvel, Gautier Grouvel, Julie Corre, Maurizio Ranieri, Samuel Cavuscens, Anissa Boutabla, Jean-François Cugnot, Raymond van de Berg, Nils Guinand, Stéphane Armand, Stéphane Armand, Angélica Pérez Fornos   +12 more
doaj   +1 more source

Controlled Interaction: Strategies For Using Virtual Reality To Study Perception [PDF]

, 2010
Immersive virtual reality systems employing head-mounted displays offer great promise for the investigation of perception and action, but there are well-documented limitations to most virtual reality systems. In the present article, we suggest strategies
Durgin, Frank H., Li, Z.
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Infant eye and head movements toward the side opposite the cue in the anti-saccade paradigm

Behavioral and Brain Functions, 2007
Background The anti-saccade task, when people must respond in the direction opposite to a visual stimulus, has been used as a marker of operation of the frontal cortical oculomotor area.
Sukigara Masune, Nakagawa Atsuko
doaj   +1 more source

Street crossing behavior in younger and older pedestrians: an eye- and head-tracking study [PDF]

, 2015
Background Crossing a street can be a very difficult task for older pedestrians. With increased age and potential cognitive decline, older people take the decision to cross a street primarily based on vehicles’ distance, and not on their speed ...
Cazzoli, D, Jäger, M, Mast, FW, Mosimann, UP, Müri, RM, Nef, T, Nyffeler, T, Scheffler, L, Zito, GA   +8 more
core   +3 more sources

Generalized head movement

Proceedings of the Linguistic Society of America, 2018
We argue for a unified account of head movement and lowering in which lowering is in essence the covert movement counterpart of head movement. This proposal is supported by the existence of successive cyclic lowering (evidenced by relative prefix formation in Ndebele), in which complex heads built by lowering have the Mirror-Principle-obeying structure
Karlos Arregi, Asia Pietraszko
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Unconstrained video monitoring of breathing behavior and application to diagnosis of sleep apnea [PDF]

, 2014
This paper presents a new real-time automated infrared video monitoring technique for detection of breathing anomalies, and its application in the diagnosis of obstructive sleep apnea.
Gravill, N., Hunter, A., Matusiewicz, S., Wang, C.-W.   +3 more
core   +1 more source